Description
Fundamentals of Osteoporosis offers a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work. Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, and histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery.- Presents a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work- Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery- Clear, concise presentations by bone biologists of the cellular and molecular mechanisms underlying osteoporosis
Table of Contents
1. The Bone Organ System: Form and Function2. The Nature of Osteoporosis3. Skeletal Heterogeneity and the Purposes of Bone Remodeling4. Osteoblast Biology5. Osteoclast Biology6. Osteocytes7. The Regulatory Role of Matrix Proteins in Mineralization of Bone8. Development of the Skeleton9. Mouse Genetics as a Tool to Study Bone Development and Physiology10. Parathyroid Hormone and Parathyroid Hormone-Related Protein11. Vitamin D: Biology, Action, and Clinical Implications12. Regulation of Bone Cell Function by Estrogens13. Androgens and Skeletal Biology: Basic Mechanisms. Phosphatonins14. Wnt Signaling in Bone15. Cytokines and Bone Remodeling16. Skeletal Growth Factors17. Intercellular Communication during Bone Remodeling



