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Advances in Radiation Biology, Volume 5 focuses on the various phases of development in radiation biology. This book discusses the radiobiological implications of statistical variations in energy deposition by ionizing radiations; fundamental physics of energy deposition; and radiological assessment of nuclear power stations. The environmental transport of released radionuclides; effects of continuous irradiation on animal populations; and radiation-induced life-shortening and premature aging are also deliberated. This text likewise covers the production of radiation damage in a heterogeneous system; radical identification by EPR; redistribution of cells through the division cycle; and iso-effect formulas. This publication is valuable to radiation biologists, including those interested in radiobiology.
Table of Contents
ContributorsContents of other VolumesThe Radiobiological Implications of Statistical Variations in Energy Deposition by Ionizing Radiations I. Introduction II. Traditional Approaches to Microdosimetry III. Fundamental Physics of Energy Deposition IV. Importance of Statistical Processes V. An Illustration of Possible Radiobiological Interpretation VI. Modeling Based on Microdosimetric Concepts ReferencesRadiological Assessment of Nuclear Power Stations I. Introduction II. Radioactivity Releases from Nuclear Power Stations III. Environmental Transport of Released Radionuclides IV. Estimation of Radiation Dose V. Assessment of the Dose Estimates VI. Future Developments ReferencesEfFects of Continuous Irradiation on Animal Populations I. Introduction II. General Designs of Field Studies III. Dosimetry IV. Effects of Continuous Irradiation on Animal Populations V. Discussion ReferencesRadiation-Induced Life-Shortening and Premature Aging I. Introduction II. Definitions III. Historical Basis for an Association of Radiation-Induced Life-Shortening and Natural Senescence IV. Evidence against the Hypothesis That Radiation-Induced Life-Shortening and Pathology are Related to Natural Senescence V. Conclusions ReferencesMolecular Mechanisms of Radiation-Induced Damage to Nucleic Acids I. Introduction II. Production of Radiation Damage in a Heterogeneous System III. Simulation of In Vivo Radiation Damage Using In Vitro Model Systems IV. Irradiation of Solid Materials V. Frozen Solutions VI. Aqueous Solutions VII. Radical Identification by EPR VIII. Radiation Products of the Purine and Pyrimidine Bases IX. Strand Breaks X. Modifications of Radiation Damage Caused by Macromolecular Structure XI. Effects of Other Free Radicals on DNA Constituents XII. Methods of Examining Direct Effects in Aqueous Systems XIII. Radiation Modifiers References BibliographyThe Four R's of Radiotherapy I. Introduction II. Repair of Sublethal Injury III. Reoxygenation IV. Redistribution of Cells through the Division Cycle V. Regeneration VI. Iso-Effect Formulas ReferencesSubject Index
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