Description
How to Scale-Up a Wet Granulation End Point Scientifically provides a single-source devoted to all relevant information on the scale-up of a wet granulation end point.Contents include a general description, problem identification, and theoretical background with supporting literature, case studies, potential solutions, and more. By outlining issues related to scale-up and end-point determination, and then using practical examples and advice to address these issues, How to Scale-Up a Wet Granulation End Point Scientifically is a valuable and essential resource for all those pharmaceutical scientists and technologists engaged in the granulation process.- Thoroughly referenced and based on the latest research and literature- Part of the Expertise in Pharmaceutical Process Technology Series edited by internationally respected expert, Michael Levin- Illustrates the most common problems related to scale-up of a wet granulation end point and provides valuable insights on how to solve these problems in a practical way
Table of Contents
1. Scale-Up Basics2. Dimensional Analysis, Principle of Similitude, Dimensionless Numbers, Comparison of attainable Froude Numbers3. Scientific scale-up procedure4. Case Studies5. Practical Considerations for End-Point Scale-Up6. List of Symbols and Dimensions, Literature Reference
