Description
Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men.This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.- Brings together more eminent investigators and clinicians to interpret developments in this growing field- Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy- There is no book on the market that covers osteoporosis in men as comprehensively as this book
Table of Contents
Section 1 Essentials of bone biology 1. The Biochemistry of Bone: Composition and Organization2. Bone Remodeling: Cellular Activities in Bone3. Assessment of Bone Turnover Using Biochemical Markers4. Fundamentals of Mineral Homeostasis5. The Mechanical Properties of Bone6. Assessment of Bone ArchitectureSection 2 Development and growth of the male skeleton7. Skeletal Growth in Males8. Pubertal Growth of the Male Skeleton9. The Effects of Sex Steroids on Bone Growth10. Nutritional Basis of Skeletal Growth 11. Physical Activity and Skeletal GrowthSection 3 Skeletal genetics12. The Genetics of Peak Bone MassSection 4 Aging and the male skeleton13. Age-Related Changes in Bone Remodeling and Micro Architecture14. Markers of Bone Remodeling and the Aging Skeleton 15. Alterations in Mineral Metabolism in the Aging Male16. Change in Bone Size and Geometry with Aging17. Aging and Bone Density18. The Effect of Age on Material PropertiesSection 5 Nutritional issues19. Calcium, Bone Strength and Fractures20. Vitamin D and Bone21. Role of Dietary Protein in Bone Growth and Bone LossSection 6 Sex steroids and the skeleton in men22. The Molecular Biology of Sex Steroids in Bone: Similarities and Differences Among the Sexes23. Estrogen and the Skeleton – Rodents24. Estrogen and the Skeleton – Humans25. Androgens and the Skeleton – Animal Models 26. Androgens and the Skeleton – Humans27. Androgen Effects on the Skeletal MuscleSection 7 Fractures in men28. Epidemiology of Fractures 29. Individualized Progress of Fractures in Men30. Physical Activity, Physical Function and Fall and Fracture Risk in Older Men31. Economic Impact of Osteoporotic Fractures (vs women)32. Adverse Health Outcomes in Men with OsteoporosisSection 8. Metabolic bone disease in men33. Idiopathic Osteoporosis34. Glucocorticoid Induced Osteoporosis35. Testicular Dysfunction36. Alcohol and Bone37. Transplantation Osteoporosis38. Management of Fractures in Men with Impaired Renal Function39. Hyperparathyroidism40. Hypercalciuria41. The Skeletal Phenotype of the Male Athlete42. Inherited and Related Disorders of Bone Matrix Synthesis in MenSection 9 Diagnostic approach43. Dual-Energy X-ray Absorptiometry (DXA) in Men44. Quantitative Ultrasound Diagnosis of Osteoporosis in Men45. Advanced Structural Assessment of Bone Using CT and MRI46. Vertebral Fracture Assessments47. The Use of Bone Biopsies in the Diagnosis of Male Osteoporosis48. Overall diagnostic strategySection 10 Therapy49. Diagnostic Thresholds for Osteoporosis in Men50. Cost-Effectiveness of Interventions to Reduce Osteoporosis-Related Fractures in Men: Current Data, Controversies, and Challenges51. Nutritional Therapy for Skeletal Health in Men52. Exercise Programs for Patients with Osteoporosis53. Calcitonin: History, Physiology, Pathophysiology and Therapeutic Applications54. Treatment of Male Osteoporosis with Bisphosphonates55. Treatment of Male Osteoporosis with Parathyroid Hormone56. Testosterone Therapy for Osteoporosis in Men57. Future Therapies: Strontium, SERMs, SARMs and New Therapies on the Horizon
