Description
Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more.- The only comprehensive book on proteolytic enzymes- Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research- Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases- Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features- Over 1000 peptidases included
Table of Contents
Aspartic PeptidasesIntroduction / Clan AA - Family A1 / Clan AA - Family A2 And Others / Other Clans of Aspartic PeptidasesGlutamic PeptidasesAsparragine Peptide LyasesMetallopeptidasesIntroduction / Clan MA subclan E - Family M1 / Family M2 / Family M3 / Families M4,M5 and M9 / Family M13 / Other families in subclan MA(E) / Clan MA subclan M - Families M10 and M11 / Family M12 subfamily A / Other families in clan MA / Clan MC / Clan MD / Clan ME / Clan MF / Clan MG / Clan MM / Clan MO / Clan MP / Clan MH / Other clans of metallopeptidases / Metallopeptidases not yet assigned to clansCysteine PeptidasesIntroduction / Clan CA - Family C1 / Other families in clan CA / Clan CD / Clan CE / Clan PA subclan C / Other clans of cysteine peptidases / Cysteine peptidases not assigned to familiesSerine and Threonine PeptidasesIntroduction / Clan PA subclan S - Family S1 / Other families in clan PA(S) / Clan SB - Family S8 / Family S53 / Clan SC - Family S9 / Other families in clan SC / Clan SE / Clan SF / Clan SH / Other clans of serine peptidases / Serine peptidases not assigned to family / Clan PB / Unsequenced serine peptidases / Peptidases of uncertain catalytic type
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