Description
The Endocannabinoidome: The World of Endocannabinoids and Related Mediators is dedicated to the latest research and studies on endocannabinoids and cannabinoid receptors to illustrate their important role in the discovery of new, endocannabinoid-related, lipid mediators. Written by leading experts across different disciplines, this book focuses on the biochemical and anlayticial aspects of novel lipid signals, their pharmacological activities and their potential utilization for the development of new and effective therapeutic strategies. The first book of its kind, The Endocannabinoidome is a meaningful reference for all those involved in experimental efforts to further the development of this field.- Explores the novel and exciting aspects of several endocannabinoid-like molecules for which researchers are still seeking a function- Discusses the novel metabolic pathways for endocannabinoids in order to explain the failure of some clinical trials with inhibitors of more conventional metabolic pathways- Incorporates pharmacology, biochemistry and potential clinical applications to provide researchers with a complete look at endocannabinoids
Table of Contents
Introduction- Non-endocannabinoid N-acylethanolamines and Monoacylglycerols: Old Molecules, New Targets- Omega-3 Polyunsaturated N-acylethanolamines: A Link Between Diet and Cellular Biology- Lipoaminoacids: A Combinatoral World of New Lipid Signals- Oxidative Metabolites of Endocannabinoids Formed by Cycloocygenase-2- N-acyldopamines and N-acylserotonins: From Synthetic Pharmacological Tools to Endogenous Multi-Target Mediators- The Pharmacology of Prostaglandin F2α Ethanolamide and Bimatoprost Reveals a Unique Feed-Back Mechanism on Endocannabinoid Actions- Prostamide F2α Biosynthesizing Enzymes- Metabolic Enzymes for Endocannabinoids and Endocannabinoid-like Mediators- Endocannabinoidomics: "Omics" Approaches Applied to Endocannabinoids and Endocannabinoid-like Mediators- Common Receptors for Endocannabinoid-like Mediators and Plant Cannabinoids
