Description
Early Vascular Aging (EVA): New Directions in Cardiovascular Protection brings together the last decade of research related to the characterization of EVA, as well as the predictive power of pulse wave velocity (PWV).The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences.Information provided is accompanied by online access to a supplemental website with video clips of anatomic specimens, cardiac imaging, and surgical procedures.- Introduces the latest information on early vascular aging (EVA), complete with summaries of recent evidence and guidelines for relevant risk factor control- Ideal reference for the study of vascular aging, pulse wave velocity, arteriosclerosis, EVA, arterial stiffness, vascular, PWV biomarkers, and cardiovascular disease- Contains all the relevant information available from different fields of knowledge (from basic biology to epidemiology) in regard to EVA- Provides evidence that leads to a new target for interventions, early vascular aging (EVA) in subjects with early onset increased arterial stiffness- Includes online access to a supplemental website with video clips of anatomic specimens, cardiac imaging, and surgical procedures
Table of Contents
Chapter 1: Historical Aspects and Biology of AgingChapter 2: Cellular and Molecular Determinant of Arterial AgingChapter 3: Changing Demography of Europe-Greying PopulationsChapter 4: Population-Based StudiesChapter 5: Lessons from Amsterdam Growth and Health Longitudinal StudyChapter 6: History and Findings of the BLSAChapter 7: Changes in Peripheral Blood Pressure with Normal and Accelerated AgingChapter 8: Changes in Arterial Stiffness with Normal and Accelerated AgingChapter 9: Changes in Central Hemodynamics, Wave Reflection and Heart-Vessel Coupling with Normal and Accelerated AgingChapter 10: Early Aging of Endothelial Function and Platelet-Vessel Wall InteractionChapter 11: The Cross-Talk between the Macro and MicrocirculationChapter 12: Blood Pressure VariabilityChapter 13: Early Vascular Aging in Children with Low Birth Weight and/or PrematurityChapter 14: Age-Induced Endothelial Dysfunction and Intima-Media ThickeningChapter 15: Glucose Metabolism, Diabetes, and the Arterial WallChapter 16: Chronic Inflammation and AntherosclerosisChapter 17: Early and Late Stages of Chronic Kidney Disease in relation to Arterial ChangesChapter 18: Polycystic Ovarian SyndromeChapter 19: Early and Late Stages of Brain DamageChapter 20: Telomere Biology and Aging Chapter 21: Traditional versus new models of Risk PredictionChapter 22: Imaging Biomarkers: Aortic Stiffness and Carotid IMT as Predictors of CV DiseaseChapter 23: Genetic Markers in Prediction of CV DiseaseChapter 24: Vascular Aging and CV DiseaseChapter 25: Lifestyle Intervention: What works?Chapter 26: Targeting BP Lowering and Sympathetic Nervous SystemChapter 27: Targeting Central BP through the Macro-Microcirculation Cross-TalkChapter 28: Treatment of Abnormalities in Glucose and Lipid MetabolismChapter 29: New Drugs under Development for Cardiovascular PreventionChapter 30: Interventions to retard Biological Aging to be ExploredChapter 31: Immuniziation, Vaccines and Immunomodulation
