Description
Allergens and respiratory pollutants is a collection of 12 authoritative papers that draws upon the collective expertise of world leaders in the fields of innate immunity, immunotoxicology and pulmonary biology. The book critically explores the biological and immunological mechanisms that contribute to immune dysfunction on exposure to allergens and the susceptibility to infectious disease on exposure to ambient pollutants. The clinical relevance of exposure to ambient airborne xenobiotics is critically discussed and collectively, this book provides an educational forum that links the health effects of environmental exposures, immune dysfunction and inflammatory airways disease.- Discusses recent advances in our understanding of cell-mediated innate immune mechanisms that occur during allergic inflammation and provides important timely coverage of diseases of concern and how such diseases are influenced by a dysfunctional immune system- Provides useful information on linking environmental 'danger signals' that provoke immune dysfunction and exacerbation of existing disease- Draws upon the collective expertise of an international college of leaders in the field, but also provides chapters that provide essential reference material
Table of Contents
List of illustrationsEditor's noteAbout the editor and contributorsChapter 1: An introduction to allergic inflammation and the innate immune sensing of dangerous ambient pollutants by the dendritic cellChapter 2: Asthma: primary immunomodulatory pathwaysChapter 3: Environmental lung injury and pattern recognition receptorsChapter 4: Asthma exacerbations: a paradigm of synergy between allergens, pollutants and virusesChapter 5: Bronchial hyperresponsiveness and lung inflammation induced by allergic immune response and oxidative stress: role of innate and adaptive immune responsesChapter 6: Effects of air pollutants on allergic sensitization through the airwayChapter 7: Particulate matter and oxidative stress: dangerous partners in inflammation, vascular dysfunction and innate immunityChapter 8: Diesel exhaust particles and the airway epithelial cell - dendritic cell interface in the control of immune homeostasisChapter 9: Role of macrophages in adverse pulmonary effects of particulate pollutantsChapter 10: Particulate air pollution and vulnerability to respiratory infections in childrenChapter 11: The intersection of respiratory syncytial virus infection, innate immunity and allergic lung diseaseChapter 12: Interactions between allergens and dendritic cells: pattern recognition receptors and their function in the pathogenesis of allergic respiratory diseasesIndex
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- 洋書電子書籍
- Strategic Defense I…
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