Full Description
This book reviews state of the art of polymeric biomaterials for regenerative medicine and highlights advances in both fundamental science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physiochemical property modulation, as well as their influence on the adhesion and performance of biomolecules, cells, and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies.
In the second edition, most of the chapters are updated according to the latest progress of this research field. A new chapter on nerve regeneration is also included.
Contents
Chapter 1. An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells.- Part I. Structural Scaffolds and Bio-activation.- Chapter 2. Polymeric and Biomimetic ECM Scaffolds for Tissue Engineering Applications.- Chapter 3. Versatile Hydrogels in Regenerative Medicine.- Chapter 4. Multilayer Microcapsules with Tailored Structures and Properties as Delivery Carriers for Drugs and Growth Factors.- Part II Biomaterials Surfaces/Interfaces and Bio-interactions. Chapter 5. Interactions of Biomaterial Surfaces with Proteins and Cells.- Chapter 6. Surface Modification of Tissue Engineering Scaffolds.- Chapter 7. Gradient Biomaterials and Their Impact on Cell Migration.- Chapter 8. Stem Cell Differentiation Mediated by Biomaterials/Surfaces.- Part III Regeneration of Some Clinic-Targeted Tissues.- Chapter 9. Cartilage Regeneration.- Chapter 10. Skin Regeneration.- Chapter 11. Regeneration of Blood Vessels.- Chapter 12. Cardiac repair and regeneration.- Chapter 13.Nerve Regeneration.
