Full Description
This book reviews the physiological and therapeutic applications of extracellular vesicles (EV) of different cell types. The initial chapter of the book focuses on their evolution, physiological functions, inter- and intra-cellular communication, and their strategic applications in defining different health disorders including aging, pathogenicity, toxicity, and drug delivery. The chapter also provides an overview of recent technologies for EV isolation, analysis, and quantification. The chapter also examines the role of EVs in viral and bacterial pathogenesis and discusses the emerging potential of EVs as diagnostic and therapeutic tools. It also discusses the emerging role of EVs including endosome-derived exosomes and fragments of the cellular plasma membrane in intercellular communication by transporting messenger RNA, microRNA (miRNA), and proteins. The book further explores the potential of membrane vesicles in the prevention, diagnosis, and treatment of inflammatory diseases,metabolic disorders, cardiovascular diseases, and neurodegenerative disorders. This book address researchers, clinicians, and doctoral and graduate students working in cellular molecular biology, cancer biology, infectious diseases, molecular medicine, biomedicine, neurobiology, microbiology, and translational medicine.
Contents
Chapter 1_Historical Perspectives of Research Trends on Extracellular Vesicles.- Chapter 2_Methods in Extracellular Vesicle Isolation, Characterization, and Production.- Chapter 3_Therapeutic Prospects of Stem Cell-Derived EVs: Upcoming Avenues, Promises and Challenges.- Chapter 4_Extracellular Vesicles in Cell-Cell Communications and Potential in Clinical Interventions.- Chapter 5_Extracellular Vesicles and Bacterial Infection.- Chapter 6_Extracellular Vesicles and Bacterial Infections in Fish.- Chapter 7_Probiotics Associated Extracellular Vesicles in Health and Diseases.- Chapter 8_Extracellular Vesicles in Viral Infection.- Chapter 9_Revolutionizing Viral Vaccine Strategies: The Dual-Action Potential of Extracellular Vesicles in Efficient Antigen Delivery and Immune Response Amplification.- Chapter 10_Extracellular Vesicles and Inflammatory Diseases.- Chapter 11_Extracellular Vesicles in Cancer Diagnosis.- Chapter 12_Extracellular Vesicles and Cancer Therapy.- Chapter 13_Exploring Extracellular Vesicles as a Potential Source of Biomarkers for the Diagnosis of Colorectal Cancer and its Current Challenges.- Chapter 14_Extracellular Vesicles and Cardiovascular Disease: Diagnostic and Therapeutic Perspective.- Chapter 15_Therapeutic Role of Extracellular Vesicles in Neurodegenerative Disorders.- Chapter 16_The Role of Extracellular Vesicles in Aging: An Overview and Implications.
