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Full Description
This reference work presents a comprehensive and authoritative overview of the rapidly evolving field of synthetic biology. It brings together the foundational concepts, technological innovations, and wide-ranging applications that define this discipline. By applying engineering principles to biological systems, synthetic biology enables the design of novel biological parts, systems, and functions. The handbook explores recent breakthroughs ranging from synthetic circuits for diagnostics and therapeutics to engineered biomaterials and biofuels, positioning itself as a valuable, one-stop reference for this interdisciplinary science.
Synthetic biology has grown into a transformative field at the intersection of biology, engineering, and computation. It allows precise control and design of biological systems through synthetic promoters, ribosome binding sites, genetic circuits, and other engineered components. These capabilities are driving innovations in health, environment, and energy.
The handbook is organized into five sections. These cover: fundamentals of synthetic biology; advances in tools and methodologies; real-world applications across diagnostics, therapy, and biotechnology; synthetic biology's role in treating human diseases; and finally, ethical, regulatory, and societal considerations. Each chapter provides accessible, well-structured insights for readers across disciplines.
This handbook is designed for a diverse audience—including researchers, students, clinicians, industry experts, and policymakers. It serves as both an introductory guide and a detailed reference, offering rich, easy-to-understand content enhanced by clarity, depth, and broad coverage. This is a foundational resource for anyone looking to engage with the future of biology.
Contents
Section I: Fundamental of synthetic biology.- Overview of synthetic biology.- Computational tools in synthetic biology.- Design and Characterization of genetic parts in Synthetic biology.- Standardization and modularity of synthetic biology.- Design and characterization of synthetic oscillators.- Section II: Advances in synthetic biology.- Design and characterization of the synthetic microbial genome.- Expansion of genetic codes and its applications.- Xeno nucleic acids and their applications.- Minimal cells.- Synthetic cells.- Cell free systems: Applications.- Gene and Genome Assembly.- De novo gene Synthesis.- Section III: Applications of synthetic biology.- Synthetic biology-based diagnostic tools.- Synthetic biology-based biosensors.- RNA-based Therapeutics.- RNA-based Vaccines.- Cell based therapy.- Section IV: Synthetic biology for human disease.- Design of chimeric antigen receptor-T therapy.- Synthetic biology for treatment of cancer.- Synthetic biology for treatment of blood disorders.- Section V: Synthetic biology ethics and regulations.- Synthetic biology for biosafety and ethics.- Synthetic biology patents and technology.- Impact of synthetic biology on society.- Regulatory aspects of synthetic biology.- Economic aspects of synthetic biology.
