Full Description
The book covers all aspects of peri-operative anesthetic management of liver transplant patients. It provides a comprehensive coverage of the relevant history, surgeons', hepatologists', intensivists' and pediatricians' perspective of the disease, its pathogenesis, clinical presentation and indication for transplant. It discusses the practical aspects like fluid management and use of vasopressors. The book is divided into sections for a better and comprehensive delivery of information. Individual sections provide up to date information on the pre-operative issues and optimisation, intra-operative care and management and post-operative critical care issues and management of all transplant patients with special emphasis on recent advances. Separate sections cover ICU care of these patients in great detail and anesthetic management of pediatric liver transplant. The book includes anesthetic techniques involved in conducting multiorgan transplant. It discusses clinical approach toa patient with acute liver failure, brain death criteria and laws and organ donor management. It also presents newer techniques and methodologies adopted in the field of liver transplant. It includes ample illustrations, flowcharts, key points in each chapter, figures and photographs. The book contains chapters focusing on post-transplant patients presenting for non-transplant surgery.
The book fills the gap in the literature for a comprehensive guide for the anesthetist performing or pursuing liver transplant, students/trainees/examinees who have a keen interest in this field and doctors dealing with such patients in critical care, donor management, pursuing general anesthesia. It is also helpful for hepatologists, intensivists and surgeons associated with liver transplant.
Contents
History of liver transplantation in Indian.- Basics Anatomy & Pathophysiology of Liver Disease.- Physiological role of liver & interpreting liver function tests.- Surgical anatomy of the liver.- Pathophysiology of chronic liver disease.- Pharmacokinetics & Pharmacodynamics of drugs in liver disease.- Viral markers and their relevance in liver disease and transplantation.- Liver Transplantation - Indications, Pre-operative Assessment and Optimization.- Physiological role of liver & interpreting liver function tests.- Surgical anatomy of the liver.- Pathophysiology of chronic liver disease.- Pharmacokinetics & Pharmacodynamics of drugs in liver disease.- Viral markers and their relevance in liver disease and transplantation.- Liver Transplantation - Indications, Pre-operative Assessment and Optimization.- Indications and contraindications for liver transplantation.- Disease Severity Scoring System in Chronic Liver Disease.- Pre-operative assessment and optimization of liver transplant patient - Ascites and Hydrothorax.- Pre-operative assessment and optimization of liver transplant patients - Cardiac issues in liver disease.- Pre-operative assessment and optimization of liver transplant patients - Renal issues.- Pre-operative assessment and optimization of liver transplant patients - Pulmonary issues.- Coagulation in liver disease.- Nutrition in chronic liver disease.- Intra-operative Course and Management.- Intra-operative management of transplant recipient - An overview.- Ischaemia reperfusion injury.- Haemodynamic monitoring in liver transplantation.- Intra-operative coagulation monitoring in liver transplant surgery.- Fluid therapy in liver transplant.- Role of vasopressors in liver transplant surgery.- Minimizing blood loss in recipient surgery.- Venovenous bypass (VVB) in liver transplantation.- Venovenous bypass (VVB) in liver transplantation.- Intra-operative complications and management.- Peri-operative assessment & management of live donor for donor hepatectomy.- Brain Death and Organ Donation.- Ethical and legal issues in donation after cardiac death (DCD).- Management of deceased donor for organ donation.- Normothermic machine perfusion.- Normothermic machine perfusion.- Acute Liver Failure.- Critical care management of acute liver failure.- Critical care management of acute liver failure.- Bridging therapies in Acute and Acute on Chronic Liver Failure.- Anaesthetic management of acute liver failure for liver transplant.
