Full Description
This book describes insight mechanisms for designing molecular probes and methods that these agents can be used for medical diagnosis in preclinical animal models via optical, MRI and PET imaging. The book has a wealth of schemes of synthesis and methods deduced from pioneers in the field, making it possible to immerse into real-world molecular imaging. Written for graduate student training and practitioners, this book will serve as a teaching material and/or reference for anyone interested in exploring the power of chemical synthesis of imaging agents.
Contents
Chapter 1: Overview of the fundamentals of chemistry for molecular probe design.- Chapter 2: Principles for the design of fluorescent dyes.- Chapter 3: Principles for the design of PET probes.- Chapter 4: Principles for the design of MRI probes.- Chapter 5: Solid-phase chemistry.- Chapter 6: Construction of molecular probes and imaging applications
