Fish Analysis for Drug and Chemicals Mediated Cellular Toxicity (Springerbriefs in Applied Sciences and Technology)

Saxena, Ajit Kumar/ Kumar, Amit

Springer Verlag, Singapore（2020/07発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 89 p.
• 言語 ENG
• 商品コード 9789811546990

Full Description

This book offers a comprehensive overview of drug and chemical cellular toxicity, especially concerning the effects of anticancer drugs (cyclophosphamide, methotrexate and phosphamidon) on chromosomes and proteins. It covers histological changes in rat testis during pre- and postnatal exposure to varied drug doses, along with laboratory findings on arsenic exposure and alcohol consumption producing neurological changes and deleterious effects on reproductive health in animals. 
The book offers essential information on the role of anticancer drug- / chemical-mediated toxicity in connection with genetic changes in the brain and reproductive health, making it a valuable guide for researchers working in the areas of cancer research, infertility, molecular diagnostics and modern drug discovery, at biochemical and toxicity laboratories, and in genetic predisposition and molecular biology in general. 

Contents

Introduction to FISH analysis and Cellular Toxicity.- Discussion on anticancer drugs and its effect on reproductive and mental health.- Structural examinations of toxic agents and the effects of dose and metabolism.- Histological  changes and its correlation to exposure to toxic agents.- Statistical based approaches to risk assessment in Drug Toxicity.- Safety Evaluations.- Interpretation and application of toxicological data.