Full Description
This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding RNAs and cardiovascular diseases, 5) Potential biomarkers and therapeutic implications, 6) Future prospects. It is particularly useful for researchers and students in the field of non-coding RNA and cardiovascular biology, as well as for cardiologists, pharmacologists and physiologists.
Contents
Section I Overview.- 1. An overview of non-coding RNAs and cardiovascular system.- Section II Bioinformatics and Interactions.- 2. Bioinformatics research methodology of non-coding RNAs in cardiovascular diseases.- 3. Online databases and non-coding RNAs in cardiovascular diseases.- 4. Interactions among non-coding RNAs involved in regulating of cardiovascular diseases.- 5. RNA-binding proteins (RBPs) and non-coding RNAs in cardiovascular diseases.- Section III Non-coding RNAs regulation in cardiovascular system.- 6. Involvement of epigenetic control and non-coding RNAs in cardiovascular system.- 7. Non-coding RNAs as Epigenetic Gene Regulators in Cardiovascular Diseases.- 8. Non-coding RNAs and physiological cardiac hypertrophy.- 9. Non-coding RNAs and cardiac regeneration.- 10. Role of non-coding RNA in diabetic cardiomyopathy.- 11. Comprehensive overview of non-coding RNAs in cardiac development.- Section IV Non-coding RNAs and Cardiovascular diseases.- 12. Non-coding RNAs and heart failure.- 13. Non-coding RNAs and pathological cardiac hypertrophy.- 14. Non-coding RNAs and cardiac aging.- 15. Non-coding RNAs and ischemic cardiovascular diseases.- 16. Non-coding RNAs and coronary artery disease.- 17. Non-coding RNAs and cardiac arrhythmias.- 18. Non-coding RNA and cardiac electrophysiological disorders.- 19. Non-coding RNAs and atrial fibrillation.- 20. Y RNAs: Biogenesis, Function and Implications for the Cardiovascular System.- 21. Translational potential of non-coding RNAs for cardiovascular disease.- Section V Potential biomarkers and Therapeutic implications.- 22. Circulating non-coding RNAs and Cardiovascular Diseases.- 23. Small interfering RNAs and RNA therapeutics in Cardiovascular Diseases.- Section VI Future Prospects.- 24. Prospective advances in non-coding RNAs investigation.
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