Nmr in Structural Biology: A Collection of Papers by Kurt Wuthrich (World Scientific Series in 20th-century Chemistry)

Wuthrich, Kurt (EDT)

World Scientific Publishing Co Pte Ltd（1995/07発売）

• 製本 Hardcover:ハードカバー版／ページ数 760 p.
• 言語 ENG
• 商品コード 9789810222420
• DDC分類 574.028

基本説明

Presents a survey of the research by the winner of Nobel Prize in Chemistry 2002 and his associates during the period 1965 to 1994.

Full Description

The volume presents a survey of the research by Kurt Wüthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.

Contents

NMR and structural biology; the avenue to three-dimensional protein structure determination in solution; establishing credibility for NMR structures of proteins; evolution of NMR structure determination with biological macromolecules 1985-94; selected NMR structure determinations; confirmational equilibria and internal mobility in proteins in solution; hydration of proteins and nucleic acids in solution; protein folding; and seven appendices.