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Full Description
Fundamentals of Epigenetics provides concise yet complete information on the many aspects of the basic and most recent concepts in epigenetics, a branch of life science that deals with the mechanisms such as DNA modifications, histone modifications, RNA modifications, small and long non-coding RNAs, chromatin remodeling, which are involved in epigenetic control of gene expression without involving variations in DNA sequences. These regulatory mechanisms lead to phenotypic variations. These epigenetic mechanisms can be exploited for crop improvement and cure of human diseases.
This book is primarily designed for undergraduate and graduate level students studying epigenetics in conventional, agricultural and medicinal universities. Teachers and researchers in any discipline of life sciences, agricultural sciences, medicine, and biotechnology, molecular epigenetics and biotechnology will also find it useful as a reference book.
Contents
1. Introduction to Epigenetics
2. DNA Modifications
3. Histone Modifications
4. Functions of Histone Modifications
5. DNA, Histone and Nonhistone Protein Modifications in Gene Expression
6. RNA Modifications in Gene Expression
7. Epigenetic Modifiers
8. Epigenetic Crosstalk and Epigenetic Signals
9. Epigenetic Inheritance
10. Long and Small Non-coding RNAs
11. MicroRNAs and Short Interfering RNAs
12. RNA-Directed DNA Methylation and Epigenetic Reprogramming, Learning and Memory
13. Chromatin Remodelling
14. Epigenetic Control of Gene Expression
15. RNA Interference
16. Epigenetic Gene Silencing
17. Epigenetics in Crop Improvement
Glossary
Subject Index
