Full Description
The innate immune system comprises the cells and mechanisms that are the first line of defence against infection by other organisms.
This book provides a comprehensive synopsis of eye diseases, their immunological mechanisms and the role of the immune cells and mediators. Beginning with an introduction to the role of the innate immune system, the following chapters discuss the different types of immune cells in the eye and their role in the etiopathogenesis of various diseases including glaucoma and age-related macular degeneration.
Edited by Manfred Zierhut, recognised expert from the University of Tuebingen Germany, this book is presented in an easy to read format, enabling practitioners to understand even the most sophisticated eye disorders from an immunological perspective.
Key points
Comprehensive synopsis of the role of the innate immune system in eye diseases
Covers different types of immune cells
Edited by internationally recognised specialist in Germany
Contents
Chapter 1: Role of the Innate Immune System
Chapter 2: Microglial Homeostasis: Lessons from the Mouse Retina
Chapter 3: Keratinocyte-Derived Antimicrobial Peptides as Effectors in Innate Skin Defence
Chapter 4: The Role of Mucins in the Innate Immune System
Chapter 5: Natural Killer Cells
Chapter 6: Role of T Cells and Dendritic Cells in Immune-Mediated Diseases
Chapter 7: Toll-like Receptors: Structure and Ligand Specificities
Chapter 8: Macrophages, Autoimmunity and Control of Tissue Damage
Chapter 9: The Innate Immune Response to Cancer
Chapter 10: Role of TNF in Host Resistance to Tuberculosis Infection: Membrane TNF is Sufficient to Control Infection
Chapter 11: Innate Immunity of the External Eye
Chapter 12: Innate Immune System and its Impact on Immune Privilege in the Eye
Chapter 13: Myeloid-Derived Cells in the Eye—Distribution, Turnover and Functional Correlates
Chapter 14: Linking the Innate and Adaptive Immune Response during the Immunopathogenesis of Dry Eye Disease
Chapter 15: Innate Immune Control of Herpes Simplex Virus Replication in the Cornea
Chapter 16: Role of the Innate Immune System in Corneal Transplantation
Chapter 17: The Innate Immune Response and Autoimmune Uveitis
Chapter 18: Innate Immunity of the Eye Glaucoma
Chapter 19: The Innate Immunity System and Age-Related Macular Degeneration
