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Full Description
Fungal
infections have taken a new spectrum due to the increased incidence of
multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat
fungal infections is also narrow because of lesser probability of discovering drugs
that would bypass affecting human cells and target fungal cells producing fewer
side effects in patients. An approach has gained prominence in research is to
look for bioactive antifungal compounds from natural to synthetic sources. It
is necessary to discover new classes of antifungals to control the recent
emergence of multi-drug resistant fungal infections. This book proposed a
details top to bottom outline of antifungal compounds derived naturally or
synthetically. The details of their modifications or synthetic analogues have
been described, helpful to understand the structure-activity relationship which
leads to new compound development in antifungal chemotherapy. Each chapter
begins with a comprehensive, top-bottom in-depth discussion of antifungal
agents with updated bibliographic references. This compendium will serve as a
companion not only for Scientists, Researchers, and Professors, Medical
Practitioners but also a valuable reference text for the university students.
Contents
1. Fungi
Fights Fungi: Tip off in Antifungal Chemotherapy.- 2. Essential
Oil and Antifungal Therapy.- 3. Antifungal
Peptides with Potential Against Pathogenic Fungi.- 4. Lipopeptides:
Status and Strategies to Control Fungal Infection.- 5. Plant
Derived Antifungal Agents: Past and Recent Developments.- 6. Recent
Advancements in Combinational Antifungal Therapy and Immunotherapy.- 7. Nanocarriers
of Antifungal Agents.- 8. Synthetic
Compounds for Antifungal Chemotherapy.- 9. Antifungal
therapy in Eye infections: New Drugs, New Trends.- 10. Antifungal
Susceptibility Testing of Dermatophytes.
