Full Description
The book "STEM CELL THERAPY FOR ORGAN FAILURES" edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present and the futuristic approach of the exciting field of stem cells and its intriguing properties involved in tissue repair and regeneration. The prime focus of this volume is to unravel the basic, advanced, therapeutic and translational approaches put-forth so far in the field of stem cells and regenerative medicine at research, pre-clinical and clinical levels. Stem cells has ushered in widespread interest and exciting possibilities for cell based therapies, albeit failures do prevail and small uncontrolled phase I/II studies are only signals generating, rather than definite proof of concept thereby limiting its applicability in curative therapeutics. Despite certain initiatives and meticulous untiring efforts, bringing this basic bench side research into advanced transitional bedside remained a challenge. Thus, this book embarked upon the expanding researches in these areas that seem decisive in improvising regenerative medical therapeutics, thereby leading to further path-breaking studies that cure all health challenges facing mankind. Overall, this book reveals the imperativeness of various stem cell sources and its utility in curative therapeutics.
Contents
PART A: Stem Cells: Science/Concepts and Database.- 1. Promises of Stem Cells in Research and Therapeutics.- 2. Considerations for Culturing and Preserving Adult Stem Cells For Therapeutics.- 3. Bioinformatics Tool-Box for Stem Cell Research and Therapeutics.- PART B: Stem Cells and Organ Systems.- Section I: Nervous System.- 4. Stem Cell Therapy and Neurologic Disorders: Bench to Bedside.- 5. Stem Cells and Neuronal Differentiation.- Section II: Cardiovascular System.- 6. Stem Cell Therapy For Cardiac Regeneration Post Myocardial Infarction.- 7. Endothelial Progenitor Cells: Its Applications in Vascular Medicine.- Section III: Musculo Skeletal System.- 8. Bone Marrow versus Dental Pulp Stem Cells in Osteogenesis.- 9. Adipose Derived Stem Cells: In Musculoskeletal Disorders.- Section IV: Hematopoietic System.- 10. Fetal Blood Research: A Brief Perspective on the Present, Past and Future of this Exciting Field.- 11. An Outline on Hematopoietic Stem Cell Transplantation.- 12. Placental Umbilical Cord Whole Blood and Nuclear Disaster Management: A Possibility.- 13. Mesenchymal Stem Cell Treatment Option to Manage Autoimmune Disorders A Technically Feasible Integration.- Section IV: Gastrointestinal System.- 14. Overview of Pancreatic Replacement of β-Cells from Various Cell Sources.- 15. Feto-Maternal Mesenchymal Stem Cell Transplantation For Treating Diabetes.- 16. Stem Cell Therapy for Acute and Chronic Liver Failure.- 17. Use of Stem Cells to Block the Activation of Hepatic Stellate Cells in Diseased Liver.- Section V: Reproductive System.- 18. Stem Cells of Reproductive System: At a Glance.- 19. Stem Cells of Human Endometrium: Trash to Treasure.- 20. Stem Cell Therapy in Premature Ovarian Disease.- 21. Breast Milk Cells: A Bliss to Neonates.
