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Full Description
Pharmaceutical chemistry has grown highly popular in the past decade. This book systematically brings together the huge amount of information available in this field for the benefit of students. The authors have taken great care to discuss every topic with clarity and simplicity. Topics have been selected keeping in mind the requirements of the students of undergraduate and postgraduate pharmacy courses at various universities. Textbook of Pharmaceutical Chemistry will help students grasp the subject easily and quickly with its lucid and methodical presentation of complicated chemical reactions and a good number of pharmaceutical applications in each category of reactions.
Contents
Heterocyclic Chemistry: Introduction • Nomenclature • Pyrrole • Furan • Thiophene • Imidazole • Oxazole • Thiazole • Pyrazole • Isoxazole • Indole • Pyridine • Pyrimidine • Quinoline • Isoquinolines • Acridine • Azepines • Phenothiazine • Polynuclear Hydrocarbons: Introduction • Important reactions of diphenyl methane • Important reactions of triphenyl methane • Important reactions of naphthalene • Structure of naphthalene • Anthracene • Important reactions of anthracene • Important reactions of phenanthrene • Some Drugs Containing Certain Heterocycles and Polynuclear Hydrocarbons • Synthetic Tools: Beckmann rearrangement • Schmidt reaction • Meerwein-ponndorf-verley (MPV) reduction • Clemmensen reduction • Birch reduction • Catalytic hydrogenation • Darzen's reaction • Reiley reaction (Oxidatiion with selenium oxide) • Oxidatiion with mercuric acetate • Oxidation with lead tetra acetate • Oxidation with perchloric acid (HCIO4) • Reduction with hydrazine • Metal hydride reduction • Reduction by sodium borohydride (NaBH4) • Fries rearrangement • Mannich reaction • Michael reaction • Stereo Chemistry: Introduction • Tetrahedral carbon atom • Elements of symmetry • Optical activity • Properties of racemic modification • Resolution or separation of racemic modification • Configuration • Configuration of the biphenyl molecule • Atropisomerism • Optical isomerism in nitrogen containing compound amines • Geometrical isomerism • Geometrical isomerism of nitrogen containing compound oximes • Hybridisation • Chemistry of Biomolecules: Carbohydrates • Glycosiders • Amino acids and proteins • Lipids • Vitamins • Terpenoids • Alakaloids • Purines
