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基本説明
Special Topic Issue: 'Journal of Molecular Microbiology and Biotechnology 2011, Vol. 21, No. 1-2'.
Full Description
Mutation provides the molecular basis for evolutionary change. Directed mutation occurs specifically in response to the stress condition that the induced mutation relieves, while adaptive mutation is defined as a mutation that occurs at variable rates depending on conditions, particularly stress conditions, that enhance these rates, but is not targeted to a specific site. Adaptive mutation is less controversial than directed mutation, but the mechanisms involved are in many cases still poorly defined. This written symposium on the nature, mechanisms and consequences of adaptive and directed mutation focuses on recent research dealing with these novel cutting-edge areas of genetics and evolution. Presenting several points of view, it will bring the reader up to date with respect to current research in the field using different experimental systems. Anyone interested in novel mechanisms of evolutionary change via mutation will find this written symposium, the first of its kind, a fascinating and essential read.
Contents
Introduction: Did Adaptive and Directed Mutation Evolve to Accelerate Stress-Induced Evolutionary Change?: Saier, M.H., Jr.; What Limits the Efficiency of Double-Strand Break-Dependent Stress-Induced Mutation in Escherichia coli?: Shee, C.; Ponder, R.; Gibson, J.L.; Rosenberg, S.M.; Fitness Effects of Mutations in Bacteria: Gordo, I.; Perfeito, L.; Sousa, A.; Stress-Induced Modulators of Repeat Instability and Genome Evolution: Fonville, N.C.; Ward, R.M.; Mittelman, D.; Transcriptional De-Repression and Mfd Are Mutagenic in Stressed Bacillus subtilis Cells: Martin, H.A.; Pedraza-Reyes, M.; Yasbin, R.E.; Robleto, E.A.; Transposon-Mediated Adaptive and Directed Mutations and Their Potential Evolutionary Benefits: Zhang, Z.; Saier, M.H., Jr.; Specific and Nonspecific Host Adaptation during Arboviral Experimental Evolution: Novella, I.S.; Presloid, J.B.; Smith, S.D.; Wilke, C.O.; Author Index; Subject Index.



