Full Description
Allergy and allergic diseases have increased in prevalence worldwide during the last decade. Relevant determinants influencing the development of allergic inflammation come from the environment and are either enhancing (e.g. environmental pollutants both indoors and outdoors) or protective (e.g. parasite infestations causing early stimulation of the immune system). In spite of considerable progress in experimental allergology and immunology, there is still a great discrepancy between theoretical knowledge and practical performance in the routine treatment of patients with allergies. The development of new therapeutic and preventive strategies for the future management of allergy is dependent on a better understanding of the pathomechanisms and molecular pathways involved. Based on an international symposium, this volume summarizes the latest findings in epidemiology, pathophysiology, and clinical aspects of allergic diseases such as asthma, food allergy, and, especially, atopic eczema. Risk factors for the development of allergies and novel treatment strategies are carefully evaluated. This update is essential reading for anyone interested in allergy: doctors working in the clinical fields of dermatology, pneumology, internal medicine, pediatrics, ENT, epidemiology and public health, as well as researchers in molecular genetics, immunobiology, food and nutrition sciences, and pharmacology.
Contents
Preface; Ring, J.; Darsow, U.; Behrendt, H.; Allergy and Environment:; Determinants of Allergy Development; Allergy in Evolution: Platts-Mills, T.A.E.; Climate Change, Environment and Allergy: Behrendt, H.; Ring, J.; The Hygiene Hypothesis Does Not Apply to Atopic Eczema in Childhood: Cramer, C.; Link, E.; Koletzko, S.; Lehmann, I.; Heinrich, J.; Wichmann, H.-E.; Bauer, C.-P.; v. Berg, A.; Berdel, D.; Herbarth, O.; Schaaf, B.; Borte, M.; Behrendt, H.; Kramer, U.; Molecular Genetics of Atopic Eczema: Ring, J.; Mohrenschlager, M.; Weidinger, S.; Pathogenesis of the Deviated Immune Response; Mechanisms of Immune Tolerance to Allergens: Fujita, H.; Meyer, N.; Akdis, M.; Akdis, C.A.; Th17 and Th22 in Skin Allergy: Cavani, A.; Pennino, D.; Eyerich, K.; IL-25 Induces Both Inflammation and Skin Barrier Dysfunction in Atopic Dermatitis: Deleuran, M.; Hvid, M.; Kemp, K.; Christensen, G.B.; Deleuran, B.; Vestergaard, C.; Angiogenesis, Lymphangiogenesis and Atopic Dermatitis: Genovese, A.; Detoraki, A.; Granata, F.; Galdiero, M.R.; Spadaro, G.; Marone, G.; What Can Dogs Bring to Atopic Dermatitis Research? Olivry, T.; Can Microbial Superantigens Influence Atopic Dermatitis Flares? Alomar, A.; Inflammation-Induced Alterations in the Skin Barrier Function: Implications in Atopic Dermatitis: Vestergaard, C.; Hvid, M; Johansen, C.; Kemp, K.; Deleuran, B.; Deleuran, M.; Clinical Aspects; Itch and Eczema: Darsow, U.; Pfab, F.; Valet, M.; Tolle, T.R.; Ring, J.; Eczema Herpeticum: Wollenberg, A.; Bone Mineral Density in Patients with Atopic Dermatitis: Haeck, I.; van Velsen, S.; de Bruin-Weller, M.; Bruijnzeel-Koomen, C.; Immunosuppressive Effect of Prolactin-Induced Protein: Sugiura, S.; Fujimiya, M.; Ebise, H.; Miyahira, Y.; Kato, I.; Sugiura, Y.; Kimura, T.; Uehara, M.; Sato, H.; Sugiura, H.; Therapy and Management; Is Food Allergy Testing Reliable in Pediatric Atopic Dermatitis? A Population-Based Study: Keck, L.E.; Simpson, E.L.; Berry, T.M.; Hanifin, J.M.; New Strategies for Dealing with Staphylococcus aureus Colonization and the Emerging Methicillin-Resistant Staphylococcus aureus Epidemic in Atopic Dermatitis: Boguniewicz, M.; Anti-IL-4 as a New Strategy in Allergy: Schmidt-Weber, C.B.; New Drug Targets in Atopic Dermatitis: Simon, D.; Simon, H.-U.; Latest Approaches to Treating Atopic Dermatitis: Paller, A.S.; Author Index; Subject Index.
