Full Description
Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this information has not been available in a single, up-to-date and succinct yet comprehensive source. The publication at hand aims at filling this gap, condensing a vast amount of information into easily accessible chapters. After a discussion of basic concepts and principles of renal tissue reactions to injurious agents using a specific cell/compartment approach, a multitude of disorders are looked at, including renal interstitial fibrosis, glomerulosclerosis, various forms of glomerulonephritis and nephropathy, amyloidosis and renal Fanconi syndrome. Some of the chapters address controversial subjects, reporting the current situation and showing areas of future potential research interest. At the end of many of the contributions, a summary is provided, often in the form of a chart to facilitate the understanding of the information and to make it most useful for didactic purposes. This book is intended for students of various disciplines, as well as clinicians and investigators and all those trying to correlate basic research information with clinical issues.
Contents
Foreword: Herrera, G.A.; Overview of Models for the Study of Renal Disease: Turbat-Herrera, E.A.; Mesangial Homeostasis and Pathobiology: Their Role in Health and Disease: Herrera, G.A. et al.; Parietal Epithelial Cells: Their Role in Health and Disease: Romagnani, P.; Role of Proximal Tubules in the Pathogenesis of Kidney Disease: Nakhoul, N.; Batuman, V.; Kidney Microvasculature in Health and Disease: Jen, K.-Y. et al.; Renal Interstitial Fibrosis: A Critical Evaluation of the Origin of Myofibroblasts: Barnes, J.L.; Glass II, W.F.; Immunopathogenesis of Idiopathic Nephrotic Syndrome: Zhang, S. et al.; Membranous Nephropathy: Cybulsky, A.V.; Prospects and Perspectives on IgA Nephropathy from Animal Models: Emancipator, S.N.; Infection-Related Glomerulonephritis: Brodsky, S.V.; Nadasdy, T.; Discovery of Genes Related to Diabetic Nephropathy in Various Animal Models by Current Techniques: Wada, J. et al.; Glomerular Basement Membrane Disorders in Experimental Models for Renal Diseases: Impact on Understanding Pathogenesis and Improving Diagnosis: Kashtan, C.E.; Segal, Y.; Experimental Models of Lupus Nephritis: Grande, J.P.; Experimental Models of Membranoproliferative Glomerulonephritis, Including Dense Deposit Disease: Vernon, K.A. et al.; Experimental Models of Vasculitis and Glomerulonephritis Induced by Antineutrophil Cytoplasmic Autoantibodies: Jennette, J.C. et al.; Monoclonal Immunoglobulin Light and Heavy Chain Deposition Diseases: Molecular Models of Common Renal Diseases: Ronco, P. et al.; Renal Amyloidosis: Current Views on Pathogenesis and Impact on Diagnosis: Herrera, G.A. et al.; Toward Understanding Renal Fanconi Syndrome: Step by Step Advances through Experimental Models: Sirac, C. et al.; Light Chain-Mediated Tubulopathies: Sanders, P.W.; HIV-Associated Nephropathy: Experimental Models: Avila-Casado, M.C. et al.; Acute Kidney Injury: Lessons from Experimental Models: Heyman, S.N. et al.; Pathogenesis of Tubular Interstitial Nephritis: Tanaka, T.; Nangaku, M.; Obstructive Uropathy: Truong, L.D. et al.; Renal Vasculature in Essential Hypertension: A Review of Some Contrarian Evidence: Tracy, R.E.; Thrombotic Microangiopathies: From Animal Models to Human Disease and Cure: Caprioli, J. et al.; Glomerular Repair: Present Status and Future Expectations: Herrera, G.A. et al.
