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Full Description
Sodium hypochlorite has long been recognized for its effectiveness as an antiseptic and disinfectant, but its practical use in medicine had been limited due to its reduced stability. However, it has been shown that the method of manufacture can make the vital difference: The ExSept solutions (Amuchina) discussed in this publication differ from other commercially manufactured solutions insofar as they are produced with the help of electrolysis, the result being a highly effective antimicrobial with very good biocompatibility. The papers in this volume concentrate on the experiences made with ExSept solutions in dialysis applications. They provide a sound understanding of how electrolytically produced sodium hypochlorite solutions differ from other commercial solutions, present different uses as both an antiseptic and disinfectant and alleviate some of the stereotypes associated with their medical use. Both in vitro controlled laboratory evaluations and clinical in vivo prospective randomized trials are introduced in this publication, making it a valuable help for clinicians working in the field of dialysis.
Contents
Preface: Ronco, C.; Mishkin, G.J.; Chemistry and Toxicology; Antisepsis: Bianchi, P.; Buoncristiani, E.; Buoncristiani, U.; Sodium Hypochlorite: History, Properties, Electrochemical Production: Ponzano, G.P.; Toxicity and Safety of Topical Sodium Hypochlorite: Bruch, M.K.; Applications in Hemodialysis; Disinfection of Dialysis Monitors: Ghezzi, P.M.; Bonello, M.; Ronco, C.; Biofilm on Artificial Surfaces: Cappelli, G.; Ricardi, M.; Ravera, F.; Lagabue, G.; Ballestri, M.; Bonucchi, D.; Bondi, M.; Compatibility of Electrolytically Produced Sodium Hypochlorite Solutions on Long-Term Implanted Dialysis Catheters: Mishkin, G.J.; Hemodialysis Catheter Exit Site Care: Astle, C.M.; Effectiveness of Sodium Hypochlorite in the Prevention of Catheter Related Infections: Cruz, D.N.; Ocampo, C.; Brendolan, A.; Menara, G.; Corradi, V.; de Cal, M.; Polanco, N.; Kuang, D.; Nalesso, F.; Crepaldi, C.; Ronco, C.; Applications in Peritoneal Dialysis; Use of Sodium Hypochlorite in Peritoneal Dialysis: The Genesis of the 'Y' Set and Beyond: Buoncristiani, U.; Buoncristiani, E.; Bianchi, P.; Exit-Site Care in Peritoneal Dialysis: Wadhwa, N.K.; Reddy, G.H.; Successful Use of Sodium Hypochlorite Pack Plus Systemic and Local Antibiotic Therapy for the Treatment of Pseudomonas Infection of Peritoneal Dialysis Catheter Exit-Site: Rodighiero, M.P.; Dell'Aquila, R.; Bonello, M.; Spano, E.; Di Loreto, P.; Nalesso, F.; Ronco, C.; Disinfection of Lines and Transfer Sets in Peritoneal Dialysis: Lew, S.Q.; Guria, A.; Various Applications in Dialysis; Amuchina 10 per cent Solution, Safe Antiseptic for Preventing Infections of Exit-Site of Tenckhoff Catheters, in the Pediatric Population of a Dialysis Program: Mendoza-Guevara, L.; Castro-Vazquez, F.; Aguilar-Kitsu, A.; Morales-Nava, A.; Rodriguez-Leyva, F.; Sanchez-Barbosa, J.L.; Risk of Peritonitis among Disadvantaged CAPD Patients in Mexico: Garcia-Garcia, G.; Tachiquin-Bautista, N.; Luquin-Arellano, V.H.; Ibarra-Hernandez, M.; Aviles-Gomez, R.; Briseno-Renteria, G.; Cueto-Manzano, A.M..
