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基本説明
Special Issue: 'Nephron 2006, Vol. 103, No. 2'.
Full Description
Progress in imaging technologies has provided extremely powerful tools to address clinically and biologically important questions in whole organ studies. Parallel to this, advances in molecular probes, transgenic approaches and new delivery techniques have allowed for the development of intravital studies that can follow and quantify events with enhanced resolution. Moreover, 3-D reconstruction has been substantially improved, and acquisition times of cross-sectional imaging techniques have been shortened. More importantly, there has also been a strong tendency towards functional imaging. Although not yet considered first-line procedures for evaluating patients with renal disease, newer cross-sectional imaging techniques may rapidly become established in clinical practice. Also discussed in this publication are advances of radionucleotide studies, which now provide enhanced imaging of renal structure, as well as newer experimental imaging methods derived from clinical techniques. Delineating the principals, characterization and potential applications, as well as imaging software programs and quantitative approaches to data analysis, this publication is an ideal update on new advances enabling more accurate diagnosis and on new experimental approaches that may become tomorrow's clinical standards.
Contents
Introduction; Advances in Imaging the Kidney and Cellular Processes: Herget-Rosenthal, S.; Molitoris, B.A.; Microscopic Imaging; Principles of Multiphoton Microscopy: Dunn, K.W.; Young, P.A.; Fluorescence Correlation Spectroscopy and Fluorescence Lifetime Imaging Microscopy: Breusegem, S.Y.; Levi, M.; Barry, N.P.; Image Processing Software for 3D Light Microscopy: Clendenon, J.L.; Byars, J.M.; Hyink, D.P.; Imaging Protein Trafficking: Brown, D.; Imaging the Embryonic Kidney: Caruana, G.; Young, R.J.; Bertram, J.F.; Imaging Podocyte Dynamics: Moeller, M.J.; Holzman, L.B.; Imaging Gene Expression: Kher, R.; Bacallao, R.L.; Quantitative Microscopic Approaches for Studying Kidney Functions: Yu, W.; Imaging Renin Content and Release in the Living Kidney: Toma, I.; Kang, J.J.; Peti-Peterdi, J.; Imaging Glomeruli in Renal Biopsy Specimens: Phillips, C.L.; Gattone, V.H., II; Bonsib, S.M.; Imaging Vascular Pathology: Sutton, T.A.; Horbelt, M.; Sandoval, R.M.; Functional Intravital Imaging of Leukocytes in Animal Models of Renal Injury: Atkinson, S.J.; Fluorescent Labeling of Renal Cells in vivo: Ashworth, S.L.; Tanner, G.A.; Radiologic Imaging; B-Mode Sonography in Acute Renal Failure: O'Neill, W.C.; Renal Doppler Sonography - Update in Clinical Nephrology: Krumme, B.; Applications of Computed Tomography in Renal Imaging: Read, S.; Allen, C.; Hare, C.; Magnetic Resonance Imaging of Renal Disease: Recent Developments and Future Applications: Fenchel, M.; Nael, K.; Herget-Rosenthal, S.; Krishnam, M.; Ruehm, S.G.; Imaging Acute Renal failure with Polyamine Dendrimer-Based MRI Contrast Agents: Dear, J.W.; Kobayashi, H.; Brechbiel, M.W.; Star, R.A.; Magnetic Resonance Imaging in Acute and Chronic Kidney Diseases: Present Status: Laissy, J.-P.; Idee, J.-M.; Fernandez, P.; Floquet, M.; Vrtovsnik, F.; Schouman-Claeys, E.; Evaluation of Intra-Renal Oxygenation by BOLD MRI: Prasad, P.V.; Review - 3D Micro CT Imaging of Renal Micro-Structural Changes: Gossl, M.; Bentley, M.D.; Lerman, L.O.; Electron Paramagnetic Resonance Imaging of Oxidative Stress in Renal Disease: Hirayama, A.; Nagase, S.; Nuclear Medicine Procedures for the Diagnosis of Acute and Chronic Renal Failure: Haufe, S.E.; Riedmuller, K.; Haberkorn, U..
