Full Description
This publication offers cutting-edge information about basic neurochemical and neuroimmunological research as well as clinical studies of immunological disarrangements and immunological dysfunctions in psychiatric disorders. The first part deals with psychoimmunological hypotheses and findings concerning mechanisms of underlying immunomodulation. The second part describes immunological characteristics of schizophrenia, depression and Alzheimer's disease. Furthermore, the clinical section presents novel considerations for immunological treatment strategies based on the reported immune patterns of some psychiatric disorders. Psychiatrists and immunologists in the clinic, and researchers in basic sciences will also find this book essential reading. Likewise, it will be relevant to graduate and undergraduate students with a special interest in the neurobiology of psychiatric disorders.
Contents
Immunomodulation - results and hypotheses: peripheral immunoregulation by adrenergic and cholinergic agonists / antagonists as studied in animal models, K. Schauenstein, et al.; function of sleep in human adaptive immunity, B. Zikorsky; leptin and psychopharmacology, T. Kraus; neopterin production and tryptophan degradation in patients with neurodegenerative diseases - link between immune activation and neuropsychiatric symptoms, B. Widner, et al; changes in the immune system in some animal models of depression, B.E. Leonard. Immunology and psychiatric disorders - Schizophrenia: new findings suggesting that mild Borna disease virus encephalitis underlies some affective or schizophrenic disorders and experimental treatments, K. Bechter; markers of cellular and humoral immune activity - a Th2-shift in schizophrenia? M.J. Schwarz, et al; immunological changes in schizophrenia - effects of the disease? B. Sperner-Unterweger, et al; immune function in schizophrenia - the role of disease and antipsychotic medication, N. Muller, et al. Immunology and psychiatric disorders: depression: immunocompetent cells in melancholic and non-melancholic major depression, M. Rothermundt, et al; effects of sleep deprivation on cytokines in healthy and depressed subjects, U. Voderholzer, et al; immunological effects of glucocorticoids in patients with major depression, A. Schuld, et al. Immunology and psychiatric disorders - Alzheimer's disease immunological alterations in Alzheimer's disease, K. Schott, K. et al; systemic alterations of soluble FAS in Alzheimer's disease, E. Richartz, et al.
