Description
(Table of content)
Chemistry of Synthetic Immunomodulant Muramyl Peptides.- I. From Freund's Adjuvant to MDP.- II. Synthesis of N-acetyl-muramyl-L-alanyl-D-isoglutamine (MDP).- III. Synthesis of Other N-acetyl-muramyl-dipeptides, Analogues and Derivatives of MDP.- IV. Synthesis of N-acetyl-muramyl-tri-, tetra-, and -pentapeptides, and of Some Analogs Bearing a Lipophilic Group at the C-terminal End.- V. Synthesis of N-acetyl-?-D-glucosaminyl-(1-4)-N-acetyl-muramyl-peptides.- VI. Synthesis of Oligomers and Conjugates of MDP.- VII. Mass Spectrometry of MDP and Analogues.- VIII. 13C-NMR Spectrometry of MDP and Derivatives.- IX. Analysis of MDP.- Addendum.- References.- Appendix: Leading References on Biological Activities of MDP and Derivatives.- The Chemistry of Longifolene and Its Derivatives..- I. Introduction.- II. Isolation, Occurrence.- III. Structure.- IV. Synthesis.- V. Isolongifolene.- VI. Reactions of Longifolene.- VII. Reactions of Isolongifolene.- VIII. Ultraviolet Absorption of Some Longifolene Derivatives.- IX. Biosynthesis.- X. Longifolene in Industry.- References.- Homoisoflavanones and Biogenetically Related Compounds..- 1. Introduction.- 2. Isolation and Identification.- 3. Structure and Nomenclature.- 4. Chemical Transformations and Syntheses.- 5. Biosynthesis.- 6. Biological Activity.- 7. Chemotaxonomy.- References.- Naturally Occurring Phenalenones and Related Compounds..- I. Introduction.- II. Phenalenones and Related Metabolites from Fungi.- III. Phenalenones and Related Metabolites in Higher Plants.- References.- Molecular Mechanisms of Enzyme-Catalyzed Dioxygenation. (An Interdisciplinary Review.).- I. Introduction.- II. Some Basic Chemistry of Molecular Oxygen.- III. Precedents for Metal-Activation of Dioxygen.- IV. Precedents for Metal Activation of OrganicSubstrates.- V. The Double Bond-Cleaving Dioxygenases.- VI. The Luciferases.- VII. Peroxidizing Dioxygenases.- VIII. Miscellaneous Dioxygenases.- IX. ?-Keto Carboxylic Acid Decarboxylating Dioxygenases.- X. Summary.- Acknowledgments.- References.- Author Index.tions.- 4.6. Alkylation and Dealkylation Reactions.- 4.7. Further Reactions of Eucomol.- 4.8. Chemistry of Brazilin and Hematoxylin.- 5. Biosynthesis.- 6. Biological Activity.- 7. Chemotaxonomy.- References.- Naturally Occurring Phenalenones and Related Compounds..- I. Introduction.- II. Phenalenones and Related Metabolites from Fungi.- A. Occurrence.- B. Structure and Chemistry.- C. Synthesis.- D. Biosynthesis.- E. Biological Activity.- III. Phenalenones and Related Metabolites in Higher Plants.- A. Occurrence.- B. Structure Determination.- C. Spectroscopic Methods.- D. Synthesis.- E. Biological Activity.- F. Biosynthesis.- References.- Molecular Mechanisms of Enzyme-Catalyzed Dioxygenation. (An Interdisciplinary Review.).- I. Introduction.- II. Some Basic Chemistry of Molecular Oxygen.- III. Precedents for Metal-Activation of Dioxygen.- 1. How Would an Iron- or Copper-Protein Interact with Molecular Oxygen?.- 2. Precedents for the Transfer of Dioxygen Within the Co-ordination Sphere.- 3. Precedents for the Reaction of Co-ordinated Dioxygen with Free Substrates.- 4. Free Forms of Activated Dioxygen Generated by Metals.- IV. Precedents for Metal Activation of Organic Substrates.- V. The Double Bond-Cleaving Dioxygenases.- 1. Ene-diol Cleaving Dioxygenases.- 2. Extradiol-Cleaving Dioxygenases.- 3. Other Double Bond-Cleaving Dioxygenases.- VI. The Luciferases.- VII. Peroxidizing Dioxygenases.- VIII. Miscellaneous Dioxygenases.- 1. External Flavoprotein Dioxygenases.- 2. Sulfur Oxidizing Dioxygenases.- 3. Inositol Dioxygenase.- 4. Nitropropane Dioxygenase.- 5. Carotene Dioxygenase.- 6. Ribulose Bisphosphate Carboxylate/Oxygenase.- IX. ?-Keto Carboxylic Acid Decarboxylating Dioxygenases.- X. Summary.- Acknowledgments.- References.- Author Index.
Contents
Chemistry of Synthetic Immunomodulant Muramyl Peptides.- I. From Freund's Adjuvant to MDP.- II. Synthesis of N-acetyl-muramyl-L-alanyl-D-isoglutamine (MDP).- III. Synthesis of Other N-acetyl-muramyl-dipeptides, Analogues and Derivatives of MDP.- IV. Synthesis of N-acetyl-muramyl-tri-, tetra-, and -pentapeptides, and of Some Analogs Bearing a Lipophilic Group at the C-terminal End.- V. Synthesis of N-acetyl-?-D-glucosaminyl-(1-4)-N-acetyl-muramyl-peptides.- VI. Synthesis of Oligomers and Conjugates of MDP.- VII. Mass Spectrometry of MDP and Analogues.- VIII. 13C-NMR Spectrometry of MDP and Derivatives.- IX. Analysis of MDP.- Addendum.- References.- Appendix: Leading References on Biological Activities of MDP and Derivatives.- The Chemistry of Longifolene and Its Derivatives..- I. Introduction.- II. Isolation, Occurrence.- III. Structure.- IV. Synthesis.- V. Isolongifolene.- VI. Reactions of Longifolene.- VII. Reactions of Isolongifolene.- VIII. Ultraviolet Absorption of Some Longifolene Derivatives.- IX. Biosynthesis.- X. Longifolene in Industry.- References.- Homoisoflavanones and Biogenetically Related Compounds..- 1. Introduction.- 2. Isolation and Identification.- 3. Structure and Nomenclature.- 4. Chemical Transformations and Syntheses.- 5. Biosynthesis.- 6. Biological Activity.- 7. Chemotaxonomy.- References.- Naturally Occurring Phenalenones and Related Compounds..- I. Introduction.- II. Phenalenones and Related Metabolites from Fungi.- III. Phenalenones and Related Metabolites in Higher Plants.- References.- Molecular Mechanisms of Enzyme-Catalyzed Dioxygenation. (An Interdisciplinary Review.).- I. Introduction.- II. Some Basic Chemistry of Molecular Oxygen.- III. Precedents for Metal-Activation of Dioxygen.- IV. Precedents for Metal Activation of OrganicSubstrates.- V. The Double Bond-Cleaving Dioxygenases.- VI. The Luciferases.- VII. Peroxidizing Dioxygenases.- VIII. Miscellaneous Dioxygenases.- IX. ?-Keto Carboxylic Acid Decarboxylating Dioxygenases.- X. Summary.- Acknowledgments.- References.- Author Index.
