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Full Description
Nothing tends so much to the advancement of knowledge as the application of a new instrument. - Sir Humphry Davy, 1778-1829 Neuroscience has become a rapidly expanding endeavor that relies on a number of other sciences, such as mathematics, physics, chemistry, engineering, computer sci ence, general biology and medicine, genetics etc. In fact, many of its recent success es result from the application of ideas and methods borrowed from these fields. In sofar, it is a true interdisciplinary undertaking. This convergence of influences ac counts for part of its enormous attractiveness and fascination to students and re searchers from diverse walks of life, or science, for that matter. It is probably fair to say that a great number of neuroscience's most creative and productive proponents have been lured into this field not only by the excitement about the possibility to un mask the secrets of the human mind, but also by the appeal of a vast unknown land needing cultivation and tools to cultivate it. Danger may arise for any science if it is dominated by methods and techniques of investigation rather than by problems to be solved and concepts to be developed. This might concentrate efforts onto the technically feasible and doable, rather than On the real issues. But, On the other hand, especially the young and growing sciences are heavily dependent on the development and application of methods, often even before a problem relying on these methods may become apparent.
Contents
1 Cytological Staining Methods.- 2 Application of Differential Display and Serial Analysis of Gene Expression in the Nervous System.- 3 Methods Towards Detection of Protein Synthesis in Dendrites and Axons.- 4 Optical Recording from Individual Neurons in Culture.- 5 Electrical Activity of Individual Neurons In Situ: Extra-and Intracellular Recording.- 6 Electrical Activity of Individual Neurons: Patch-Clamp Techniques.- 7 Microiontophoresis and Pressure Ejection.- 8 An Introduction to the Principles of Neuronal Modelling.- 9 In Vitro Preparations.- 10 Culturing CNS Neurons: A Practical Approach to Cultured Embryonic Chick Neurons.- 11 Neural Stem Cell Isolation, Characterization and Transplantation.- Chapter12 In Vitro Reconstruction of Neuronal Circuits: A Simple Model System Approach.- 13 Grafting of Peripheral Nerves and Schwann Cells into the CNS to Support Axon Regeneration.- 14 Cell and Tissue Transplantation in the Rodent CNS.- 15 Histological Staining Methods.- 16 Optical Recording from Populations of Neurons in Brain Slices.- 17 Recording of Electrical Activity of Neuronal Populations.- 18 Time and Frequency Domain Analysis of Spike Train and Time Series Data.- 19 Information-Theoretical Analysis of Sensory Information.- 20 Information-Theoretical Analysis of Small Neuronal Networks.- 21 Linear Systems Description.- 22 Nonlinear Analysis of Neuronal Systems.- 23 Dynamical Stability Analyses of Coordination Patterns.- 24 Detection of Chaos and Fractals from Experimental Time Series.- 25 Neural Networks and Modeling of Neuronal Networks.- 26 Acquisition, Processing and Analysis of the Surface Electromyogram.- 27 Decomposition and Analysis of Intramuscular Electromyographic Signals.- 28 Relating Muscle Activity to Movement in Animals.- 29 Long-term Cuff ElectrodeRecordings from Peripheral Nerves in Animals and Humans.- 30 Microneurography in Humans.- 31 Biomechanical Analysis of Human and Animal Movement.- 32 Detection and Classification of Synergies in Multijoint Movement with Applications to Gait Analysis.- 33 Magnetic Stimulation of the Nervous System.- 34 In-vivo Optical Imaging of Cortical Architecture and Dynamics.- 35 Electroencephalography.- 36 Modern Techniques in ERP Research.- 37 Magnetoencephalography.- 38 Magnetic Resonance Imaging of Human Brain Function.- 39 Positron Emission Tomography of the Human Brain.- 40 Magnetic Resonance Spectroscopy of the Human Brain.- 41 Monitoring Chemistry of Brain Microenvironment: Biosensors, Microdialysis and Related Techniques.- 42 Invasive Techniques in Humans: Microelectrode Recordings and Microstimulation.- 43 Psychophysical Methods.- 44 Analysis of Behavior in Laboratory Rodents.- 45 Data Acquisition, Processing and Storage.
