Bioactive Heterocycles V (Topics in Heterocyclic Chemistry) 〈Vol. 11〉

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Bioactive Heterocycles V (Topics in Heterocyclic Chemistry) 〈Vol. 11〉

Khan, M. T. H. (EDT)

ウェブストア価格 ¥48,939（本体¥44,490）
Springer（2007/11発売）
外貨定価 US$ 219.99
ポイント 444pt

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製本 Hardcover:ハードカバー版／ページ数 310 p.／サイズ 107 illus.
言語 ENG
商品コード 9783540734055
DDC分類 547

基本説明

Contents - Functionalization of Indole and Pyrrole Cores via Michael Type Additions.- Chemistry of the Welwitindolinones.- Antioxidant Activities of Synthetic Indole Derivatives and Possible Activity Mechanisms.- and more.

Full Description

This volume contains 10 chapters. The contributions are from researchers - mousintheirrespective?eldsandthechapterscontainhighqualityreviewson topics related to the chemo-biologicalstudies of several different heterocyclic groups. The ?rst chapter from Saracoglu reviews the functionalization of indoles andthepyrrolesviaMichaeladditions,asthesecompoundshavepotential for their biologicalactivities. InsecondchapterMen' endezreviewsthechemistryofthewelwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis andrecent strategiesforthesynthesisoflignans.Lignansareaveryimportant classofmolecules,astheyhaveaverydiversespectrumofbiologicalactivities, such as antitumour, antiviral, hepatoprotective, antioxidant, antiulcer, an- allergen, anti-platelet, and anti-osteoporoticactivities. InnextchapterSuzen .. describestheantioxidantactivitiesofsyntheticindole derivatives and their possible mechanisms of action. Inchapter?veGonz' alezetal.presentsacomprehensivereviewonthech- istry and biology of the quinoxaline 1,4-dioxide and phenazine 5,10-dioxide typemolecules.Theyalsodiscussthemodeofaction,structure-activitystudies andother relevant chemical andbiologicalproperties forsuch molecules.
Inthechaptersix,Khanbrie?ydiscussestheanti-angiogenicandtelomerase inhibitory activities of quinoline and its analogues. Liuet al.,inchapterseven, brie?y reviewssomeaspects ofstudies ofbio- tive marine sponge furanosesterterpenoids from the last 10 years, including their totalsyntheses. Pujol et al. in chapter eight, reviews the chemistry, origin and antiviral activities of naturally occurring sulfated polysaccharides for the prevention and controlof viral infections such as HIV-1 and -2, human cytomegalovirus (HCMV), dengue virus (DENV), respiratory syncytial virus (RSV), and - ?uenza Avirus. InchapternineHamdietal.describesthesynthesisandbiologicalactivities of the heterocyclicand vanillin ether coumarins. In the last chapter, Orhan et al. reviews their recent ?ndings on antiviral and antimicrobial heterocyclic compounds fromTurkish plants. Tromso,Norway 2007 Mahmud Tareq Hassan Khan Contents FunctionalizationofIndoleandPyrroleCores viaMichael-TypeAdditions N.Saracoglu ...1 ChemistryoftheWelwitindolinones J.C.Menendez ...63 LignansFrom TaxusSpecies G.Topcu*O.Demirkiran...103 AntioxidantActivities ofSyntheticIndoleDerivatives andPossibleActivity Mechanisms S.Suzen...1
45 Quinoxaline 1,4-DioxideandPhenazine5,10-Dioxide.