Full Description
The underlying mechanism and clinical application of T cell vaccination in experimental and human autoimmune diseases is the main feature of this text. An overview of recent advances on the subject, in particular with relevance to recent clinical trials demonstrating the therapeutic potential of T cell vaccination in human autoimmune diseases. Aspects covered by the discussion include: the potential mechanisms involved in human autoimmune pathologies; the functional and structural characteristics of pathogenic T cells and their relevance in designing specific immune intervention; the practical procedure used in recent T cell vaccination trials; and the T-T interactions induced by T cell vaccination.
