Pediatric Bone Marrow (2004. 320 p. w. 530 ill. (mostly col.).)

Pediatric Bone Marrow (2004. 320 p. w. 530 ill. (mostly col.).)

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  • 製本 Hardcover:ハードカバー版/ページ数 320 p., 530 illus.
  • 商品コード 9783540442059

基本説明

It illustrates the morphology of the peripheral blood, bone marrow aspirate and bone marrow biopsy.

Full Description


No other book covers the pathology of the bone marrow in children as extensively as Pediatric Bone Marrow. It provides a wide background for the understanding of bone marrow disease in children and its difference from that of the adult population. The text illustrates the morphology of the peripheral blood, bone marrow aspirate and bone marrow biopsy. It is useful for the diagnosis of pediatric disorders in the bone marrow, making it an ideal guide for pediatric pathologists, hematologists, oncologists and medical technologists or any physician involved in the diagnosis of pediatric bone marrow disorders.

Table of Contents

    Normal Bone Marrow                             1  (15)
References 13 (2)
Inherited Bone Marrow Failure 15 (32)
Introduction 15 (1)
Inherited Hematopoietic Syndromes 15 (4)
Associated with Pancytopenia
Fanconi Anemia 15 (1)
Laboratory Findings 16 (2)
Dyskeratosis Congenita 18 (1)
Laboratory Findings 18 (1)
Shwachman-Diamond Syndrome 18 (1)
Laboratory Findings 18 (1)
Congenital Amegakaryocytic 19 (1)
Thrombocytopenia
Laboratory Findings 19 (1)
Rare Familial Marrow Failure Syndromes 19 (1)
Inherited Hematopoietic Syndromes 19 (1)
Associated with Single Cytopenia
Diamond-Blackfan Anemia 19 (1)
Laboratory Findings 19 (1)
Congenital Dyserythropoietic Anemias 20 (9)
Severe Congenital Neutropenia 24 (1)
Laboratory Findings 24 (3)
Cyclic Neutropenia 27 (1)
Laboratory Findings 27 (1)
Chronic Benign Neutropenia 28 (1)
Thrombocytopenia with Absent Radii 28 (1)
Laboratory Findings 28 (1)
Inherited Disorders of the Leukocytes 29 (5)
Associated with Change in their Morphology
Pelger-Huet Anomaly 29 (1)
May-Hegglin Anomaly 29 (1)
Chediak-Higashi Syndrome 30 (2)
Alder-Reilly Anomaly 32 (1)
Other Morphological Abnormalities 32 (2)
Inherited Immunodeficiency 34 (2)
Reticular Dysgenesis (Alymphocytic 34 (1)
Neutropenia)
Laboratory Findings 34 (1)
X-Linked Agammaglobulinemia (Bruton 35 (1)
Agammaglobulinemia)
Laboratory Findings 35 (1)
Cartilage-Hair Hypoplasia 35 (1)
Laboratory Findings 35 (1)
Wiskott-Aldrich Syndrome 35 (1)
Laboratory Findings 36 (1)
Omenn Syndrome 36 (1)
Laboratory Findings 36 (1)
Inherited Sideroblastic Anemias 36 (5)
Laboratory Findings 37 (1)
δ-Aminolevulinate Synthase 38 (1)
(ALAS2) Deficiency
Pearson Syndrome 38 (1)
Osteopetrosis 38 (1)
Laboratory Findings 39 (2)
References 41 (6)
Macrophage-and Dendritic-Cell-Related 47 (24)
Disorders Including the Lysosomal Storage
Disorders
Introduction 47 (1)
Storage Disorders 48 (9)
Gaucher Disease 48 (1)
Laboratory Findings 48 (2)
Niemann-Pick Disease 50 (1)
Laboratory Findings 50 (2)
Wolman Disease 52 (1)
Fabry Disease 52 (1)
Sialidoses 52 (1)
Gangliosidosis GM1 and GM2 53 (1)
Fucosidosis 53 (1)
α-Mannosidosis 53 (1)
Glycogen Storage Diseases 54 (1)
Mucopolysaccharidosis 54 (1)
Cystinosis 55 (1)
Primary Hyperoxaluria 55 (1)
Sea-blue Histiocytosis 55 (2)
Histiocytosis 57 (7)
Langerhans Cell Histiocytosis 59 (2)
Laboratory Findings 61 (1)
Xanthoma Disseminatum 62 (2)
Macrophage-Related Disorders 64 (4)
Hemophagocytic Syndrome 64 (4)
Laboratory Findings 68 (1)
References 68 (3)
Bone Marrow Infections 71 (30)
Introduction 71 (1)
Infection-Associated Hemophagocytic 72 (1)
Syndrome
Granulomas 72 (1)
Bacterial Infections 72 (5)
Mycobacteria 75 (2)
Ehrlichiosis 77 (1)
Fungus 77 (3)
Viruses 80 (15)
Human Parvovirus B19 81 (4)
Epstein-Barr-Virus 85 (3)
Cytomegalovirus 88 (1)
Human Immune Deficiency Virus 89 (3)
Human Herpesvirus Type 6 92 (2)
Other Viruses 94 (1)
Parasites 95 (2)
Malaria 95 (1)
Other Parasites 96 (1)
References 97 (4)
Bone Marrow Metastases 101(32)
Introduction 101(3)
Laboratory Findings 102(2)
Neuroblastoma 104(11)
Laboratory Findings 112(3)
Rhabdomyosarcoma 115(4)
Laboratory Findings 118(1)
Ewing Family of Tumors 119(2)
Laboratory Findings 119(2)
Desmoplastic Small Round-Cell Tumor 121(2)
Central Nervous System 123(2)
Laboratory Findings 123(2)
Other Metastatic Tumors 125(4)
References 129(4)
Hematologic Manifestations of Trisomy 21 133(18)
Introduction 133(6)
Laboratory Findings 133(6)
Acute Megakaryoblastic Leukemia (FAB M7) 139(8)
Introduction 139(1)
Laboratory Findings 139(3)
Cytochemistry and Immunocytochemistry 142(3)
Electron Microscopy 145(1)
Cytogenetic and Molecular Genetics 145(2)
References 147(4)
Myelodysplastic Syndromes 151(28)
Myelodysplastic and Myeloproliferative 151(1)
Disorders
Introduction 151(1)
Myelodysplastic Syndromes 152(1)
Juvenile Myelomonocytic Leukemia 152(10)
Laboratory Findings 153(3)
Monosomy 7 Syndrome 156(2)
Unclassifiable Myelodysplastic Syndromes 158(1)
MDSs that Fit the FAB Classification in 159(2)
Children
Laboratory Findings 161(1)
Myeloproliferative Disorders 162(14)
Chronic Myelogenous Leukemia 162(1)
Laboratory Findings 163(4)
Chronic Neutrophilic Leukemia 167(1)
Polycythemia Disorders 168(1)
Polycythemia Vera 168(1)
Laboratory Findings 168(1)
Essential Thrombocythemia 169(1)
Laboratory Findings 169(1)
Hypereosinophilic Syndrome / Chronic 170(2)
Eosinophilic Leukemia
Laboratory Findings 172(1)
Systemic Mastocytosis 173(1)
Laboratory Findings 174(2)
References 176(3)
Acute Myeloid Leukemia 179(36)
Introduction 179(1)
Acute Myelogenous Leukemia 180(2)
Laboratory Findings 180(2)
Acute Myeloid Leukemia with Minimal 182(2)
Differentiation (FAB Mo)
Acute Myeloid Leukemia without Maturation 184(1)
(FAB M1)
Acute Myeloid Leukemia with Maturation 185(4)
(FAB M2)
Acute Promyelocytic Leukemia (FAB M3) 189(6)
Acute Myelomonocytic Leukemia (FAB M4) 195(3)
Acute Monoblastic Leukemia (M5) 198(3)
Acute Erythroleukemia (M6) 201(2)
Acute Megakaryoblastic Leukemia (M7) 203(1)
Acute Basophilic Leukemia 203(2)
Minimal Residual Disease 205(1)
Therapy-Related Acute Leukemia 205(2)
Congenital Leukemia 207(3)
Recurrent Chromosomal Abnormalities 210(1)
Acute Leukemia of Ambiguous Lineage 211(1)
References 211(4)
Acute Lymphoblastic Leukemia and Lymphoma 215(32)
Introduction 215(1)
Acute Lymphocytic Leukemia / 216(21)
Lymphoblastic Lymphoma
Laboratory Findings 216(21)
Minimal Residual Disease 237(1)
Lymphomas 237(6)
Non-Hodgkin Lymphomas 238(1)
Large-Cell Lymphomas 238(1)
Anaplastic Large-Cell Lymphoma 239(1)
Laboratory Findings 239(2)
Hodgkin Lymphoma 241(1)
Laboratory Findings 241(2)
References 243(4)
Anemias 247(34)
Introduction 247(2)
Microcytic Anemias 249(3)
Iron Deficiency Anemia 249(1)
Laboratory Findings 249(3)
Macrocytic Anemias 252(2)
B12 and Folic Deficiency 252(1)
Laboratory Findings 252(2)
Normocytic Anemias 254(1)
Hemolytic Anemias 255(3)
Hereditary Hemolytic Anemias 258(6)
Red Blood Cell Membrane Disorders 258(1)
Hereditary Spherocytosis 258(1)
Laboratory Findings 259(2)
Hereditary Elliptocytosis Syndromes 261(1)
Laboratory Findings 262(2)
Other Inherited Disorders of the 264(1)
Red-Cell Membrane
Hereditary Anemias Due to Hemoglobin 264(5)
Abnormalities
Sickle Cell Anemia 264(1)
Laboratory Findings 264(2)
Thalassemia Syndromes 266(2)
β-Thalassemias 268(1)
Laboratory Findings 268(1)
α-Thalassemias 268(1)
Acquired Hemolytic Anemia 269(3)
Hemolytic Disease of Newborn 269(1)
Laboratory Findings 269(1)
Autoimmune Hemolytic Anemia 270(1)
Laboratory Findings 271(1)
Acquired Non-Immune Hemolytic Anemias 272(1)
Paroxysmal Nocturnal Hemoglobinuria 272(1)
Transient Erythroblastopenia of Childhood 272(1)
Aplastic Anemia 273(4)
Laboratory Findings 273(4)
References 277(4)
Subject Index 281