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基本説明
Provides complete coverage in Biocatalysis, a major topic in Chemistry. Covers all important reactions, including C-C coupling reactions, oxidation reactions and many more. New trends for the optimization of enzymatic catalysis e.g., directed evolution and medium engineering are highlighted.
Full Description
Perfect for biochemists, synthetic and organic chemists, this book covers all important reactions, including C-C coupling reactions, oxidation reactions and many more.
Divided into two parts, the first section on methodology presents new innovative methods for enzymatic catalysis optimization, including such new trends as medium engineering, directed evolution and computer-aided prediction of enantioselectivity. The second and main section deals with applications to synthesis, showing important reaction types and their applications. Only those reactions with very high selectivity are presented, allowing readers to improve their own reaction yields.
Contents
METHODOLOGY
Medium Engineering:
Directed evolution:
The search for new enzymes:
SYNTHETIC APPLICATIONS
Dynamic Kinetic Resolutions:
Deracemization and Enantioconvergent Processes:
Transesterification and hydrolysis of carboxylic acid derivatives, alcohols and epoxides
Aminolysis and ammonolysis of carboxylic acid derivatives:
Reduction Reactions:
Oxidation Reactions:
Making and breaking C-C bonds: