- ホーム
- > 洋書
- > ドイツ書
- > Mathematics, Sciences & Technology
- > Medicine & Pharmacy
- > pharmacy, pharmacology, toxicology
基本説明
All aspects from developmental biology to such specific topics as medical applications of recombinant Epo, receptor biology, mechanisms of Epo activity, and more.
Description
(Text)
Die neuesten Erkenntnisse über Erythropoietin, seine Wirkung und medizinische Einsatzmöglichkeiten wurden in diesem Band zusammengetragen. Zahlreiche Abbildungen und Farbtafeln lassen verschiedenste Aspekte von der Entwicklungsbiologie, den Wirkmechanismen und Struktur-Aktivitäts-Beziehungen bis zur Anwendung von rekombinantem Epo und anderen therapeutisch relevanten Themen lebendig werden.
(Text)
The use of Epo in medical practice is increasing constantly. It has revolutionized how we think of blood transfusion in medicine and surgery. Moreover, it has become widely known to scientists, physicians, biotech and pharmaceutical executives and the general public. Additionally, the past ten years have seen important advances in our knowledge and understanding of its action both within and outside of the hematopoietic system.Until now, there has been no single source that contains up-to-date information on Epo addressing the array of subjects that this book presents.The book covers all aspects from developmental biology to specific topics such as medical applications of recombinant Epo, receptor biology, mechanisms of Epo activity, structure/activity relationship, disease states and important actions on non-hematopoietic organs and tissues, including the central nervous system, heart, gastrointestinal tract, reproductive organs and endothelium.
(Table of content)
From the contents:
1. Introduction and History2. Developmental Biology of Erythropoiesis and Erythropoietin Production3. Regulation of the Erythropoietin Gene: A Paradigm for Hypoxia Dependent Genes4. Physiology and Metabolism of Erythropoietin 5. Biochemistry and Protein Structure 6. Receptor Biology and Signal Transduction 7. Clinical Disorders of Erythropoietin and its Receptor8. Recombinant Erythropoietin and the Treatment of Anemia9. Function of Erythropoietin Outside of Hematopoiesis10. Bioanalytics, doping11. Future developments-experimental therapeutics
