Full Description
TRP channels play a key role in sensory physiology and have been the focus of intensive investigation in recent years. The proposed book will be a comprehensive, detailed overview of the ways in which TRP channels are involved in a wide variety of sensory modalities. Authors will explore the involvement of TRP channels in photo transduction (sight), chemotransduction (taste and odor), mechanotransduction (touch and hearing), thermo transduction (the sensation of temperature) and pain perception. Furthermore, the book will include some grounding chapters such as one on the history of TRP channel research, one on the biophysical characteristics of the proteins and one on trafficking and post-translational regulation.
Contents
Preface.- Introduction.- Biophysical and molecular features of thermo sensitive TRP channels involved in sensory transduction.- Pharmacology of TRP channels.- Modulation of TRP channels by N-glycosylation and Phosphorylation.- TRP channels in visual transductions.- TRP channels in transduction for responses to odorants and pheromones.- TRP channels as targets for modulation of taste transduction.- TRP channels and mechanical transduction.- TRP channels in the sensation of heat.- TRP channels in cold transduction.- Mathematical modeling of TRPM8 and the cold thermoreceptors.
