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Full Description
In the last few years, rapid progress has taken place in our understanding of the developmental biology of GH secretion and the pivotal role it plays in growth. This book keeps the reader updated on the most important developmental aspects and influences leading to changes in terms of clinical views. In ten chapters, well-known scientists and clinicians cover some of the most important progress made in recent times. The first chapters discuss pituitary gland development and imaging in detail followed by a comprehensive presentation of the genetics of the GH axis. Further chapters present a detailed overview of the epigenetics and bioinformatics of GH. This collection of up-to-date investigative data and reviews is of relevance not only to scientists involved in endocrinology but also to any physician interested in growth and development.
Contents
Preface: Mullis, P.-E.; Pituitary Gland Development: An Update: Bancalari, R.E.; Gregory, L.C.; McCabe, M.J.; Dattani, M.T.; Pituitary Gland Imaging and Outcome: Di Iorgi, N.; Morana, G.; Gallizia, A.L.; Maghnie, M.; Spectrum of Insulin-Like Growth Factor Deficiency: Wit, J.M.; Oostdijk, W.; Losekoot, M.; Downstream Insulin-Like Growth Factor: Pfaffle, R.; Kiess, W.; Klammt, J.; New Detection Methods of Growth Hormone and Growth Factors: Bidlingmaier, M.; Imprinted Anomalies in Fetal and Childhood Growth Disorders: The Model of Russell-Silver and Beckwith-Wiedemann Syndromes: Netchine, I.; Rossignol, S.; Azzi, S.; Brioude, F.; Le Bouc, Y.; Bioinformatics Tools and Databases for the Study of Human Growth Hormone: Pandey, A.V.; Growth Hormone and Cell Growth: Waters, M.J.; Brooks, A.J.; From Endoplasmic Reticulum to Secretory Granules: Role of Zinc in the Secretory Pathway of Growth Hormone: Petkovic, V.; Miletta, M.C.; Mullis, P.-E.; Isolated Growth Hormone Deficiency Type 2: From Gene to Therapy: Miletta, M.C.; Lochmatter, D.; Pektovic, V.; Mullis, P.-E.; Author Index / Subject Index.
