Full Description
Autoimmune and rheumatic diseases are two close allies. Differential diagnosis of both disease groups can be cumbersome since the clinical signs of rheumatic and infectious disorders are very similar. This book addresses the fact that infectious disease can either mimic or complicate rheumatic diseases. In the first part, cases of with standard rheumatic symptoms patients triggered by infections and differential diagnosis are presented. The second part is dedicated to the complications of rheumatic disease infections. Standard patient cases are presented as well as risk factors, clinical features and microbial spectra. Further chapters inform about the impact of anti-rheumatic and immunomodulatory drug therapies (incl. biological agents) on infectious risk, the specific aspects of vaccination during immunosuppressive therapy and issues about the infectious risk and chemoprophylaxis during orthopedic surgery. This book provides clinicians a detailed insight between rheumatic and infectious disease.
Contents
Part I. Infectious diseases mimicking rheumatic disease Monarthritis Case 1: Septic arthritis with S. aureus Case 2: Tuberculous arthritis Common infectious causes (bacteria) Rare causes (Borrelia, Mycobacteria, Fungi) Polyarthritis Case 3: Parvovirus-induced arthritis Case 4: Arthritis associated with gut bacteria Case 5: Viral causes (Parvo,Rubeola) Bacterial causes Other (fungi) Vasculitis Case 6: Hepatitis C -- associated vasculitis Case 7: Hepatitis B associated Panarterritis nodosa Case 8: Viral-induced vasculitis Case 9: Syphilitic aortitis Viral causes of vasculitis Bacterial infections associated with vasculitis Other Other Symptoms mimicking rheumatic disease Case 10: EBV-infection presenting as alveolitis Case 11: Viral Myositis Case 12: CNS vasculitis Part II. Infectious diseases complicating rheumatic disease Case 13: CMV-infection in Wegner's granulomatosis Case 14: Pulmonary infection in lung fibrosis Case 15: S.aureus septic polyarthritis under anti-TNF therapy Case 16: Tuberculous meningitis in a SLE patient Case 17: Listeria monarthritis under biologic therapy Case 18-20: 3 additional cases General considerations Vaccination in patients with rheumatic diseases Traditional anti-rheumatic drugs associated with a high risk of infectious complications Corticosteroids Cyclophosphamide Cyclosporin A Infections in the era of biologic drugs TNF-blocking drugs IL-1ra Rituximab Abatacept Tocilizumab
