Full Description
This fully revised 4th edition addresses the pathophysiology of vascular diseases encountered in vascular surgical practice. The principles of assessment and management of these conditions is also addressed. Many of the topics are not addressed or are inadequately addressed in clinical textbooks.
The book is pitched at trainees in vascular surgery and clinical vascular surgeons and is of use to medical students and basic surgical trainees.
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Contents
The homeostatic functions of the endothelial cells and their disfunction in peripheral artery disease.- Pathophysiology of atherosclerosis.- Imaging of atherosclerotic plaque.- Current and Emerging Therapies for Atherosclerosis.- Pathophysiology of Angiogenesis and its Role in Vascular Disease.- Vascular Biology of smooth muscle cells and arterial restenosis.- Vascular Haemodynamics.- Computational Fluid Dynamics in the arterial system: Implications for vascular disease and treatment.- Physiological Haemostasis.- Hypercoagulable States.- Platelets as Mediators and Therapeutic Targets in Cardiovascular Diseases.- An overview of abdominal aortic aneurysm pathology, and progress towards a medical therapy.- Pathophysiology and management of hereditary aneurysmal aortopathies.- Classification and Principles of Management of Descending Aortic Pathologies.- Biomarkers in Vascular Disease.- Pathophysiology and Principles of Management of Vasculitis and Fibromuscular Dysplasia.- Sepsis and Septic shock.- Pathophysiology of Reperfusion Injury.- Abdominal compartment syndrome and open abdomen treatment.- Pathophysiology and management of extremity compartment syndromes.- Pathophysiology of varicose veins, chronic venous insufficiency and venous ulceration.- Pathophysiology of Wound Healing.- Pathophysiology and principles of management of diabetes-related foot complications.- Pathophysiology and Principles of Management of Vascular Malformations.- Lymphoedema.- Graft Materials - Present and Future.- Vascular Graft Infections.- Radiation Physics and Biological Effects of Radiation in Vascular Surgery.- Radiation Stewardship: Radiation Exposure, Protection and Safety in Contemporary Endovascular Practice.- Multifaceted applications of Artificial Intelligence in Vascular Surgery.
