Full Description
This book focuses on the clinical and preclinical research on traumatic brain injuries where age at time of injury (young versus aged) reveals both parallel and divergent findings at the molecular, cellular, and behavioral levels with insights into alterations in brain structure and function and the implications for recovery. The authors address the hurdles that have been overcome, consider new directions inspired by the most recent research, and the value of data sharing and evidenced based-practice. Traumatic Brain Injuries: Tackling the Unique Terrain of the Injured Young and Aged Brain explores the challenges imposed by an injury that not only causes tissue damage but disrupts brain development and may incite pathological events in the aging brain. With the proliferation of the research literature in traumatic brain injuries, this is the time for a book that surveys the landscape and assesses where the field is headed and what is needed moving forward.
Contents
Preface.- Intracranial Pressure and its related parameters in the management of severe pediatric traumatic brain injury.- Evaluation and Management of Traumatic Brain Injuries in the Pediatric Intensive Care Unit.- Neuroimaging correlates of functional outcome following pediatric TBI.- Sleep-Wake Disorders Among Older Adults Following Traumatic Brain Injury.- Dementia and Depression Among Older Adults Following Traumatic Brain Injury.- The effects of early life history of TBI on the progression of normal brain aging with implications for increased dementia risk.- Pediatric Traumatic Brain Injury: Models, Therapeutics, and Outcomes.- The Emerging Landscape of the Cerebellum after a Pediatric Traumatic Brain Injury- From Diaschisis to Sociality.- Chronic Stress in Early development and Effects on Traumatic Brain Injury Outcome.- Sex and age-at-injury as determinants of social behavior outcomes after TBI.- Cognition and Behavior in the Aging Brain Following TBI: Surveying the Preclinical Evidence.- The Neuroimmune Interface: Age-related Responses to Traumatic Brain Injury.- Age at injury as a modifier of pre-clinical TBI behavioral, neuropathological and inflammatory outcomes.- Index.
