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Full Description
The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies, discussed both classic and the most recent imaging approaches for detection, early diagnosis and treatment of ovarian cancer. This volume, Cell & Molecular Biology of Ovarian Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to ovarian cancer. Taken together, these two volumes form one comprehensive and invaluable contribution to the literature.The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies, discussed both classic and the most recent imaging approaches for detection, early diagnosis and treatment of ovarian cancer. This volume, Cell & Molecular Biology of Ovarian Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to ovarian cancer. Taken together, these two volumes form one comprehensive and invaluable contribution to the literature.
Contents
Microtubule-targeting agents: disruption of the cellular cytoskeleton as a backbone of ovarian cancer therapy.- Tubulin complexity in cancer and metastasis.- The impact of centrosome pathologies on ovarian cancer development and progression with a focus on centrosomes as therapeutic target.- Drug-resistant epithelial ovarian cancer: current and future perspectives.- The role of the human microbiome in epithelial ovarian cancer.- Insights into the microbial composition of intratumoral, reproductive tract, and gut microbiota in ovarian cancer patients.- The impact of mitochondria in ovarian cancer cell metabolism, proliferation, and metastasis.
