Full Description
This book provides that knowledge needed to introduce individuals to the most important research and content on nanotoxicology in nanobiomedicine. Nanotechnology is helping to considerably improve, even revolutionize many technology and industry sectors: information technology, homeland security, medicine, transportation, energy, food safety, and environmental science, among many others. There is an urgent need for a general reference textbook that presents the most recent information on the toxicity and its effects in all these sectors, biomedicine in particular. It includes historical information, nanotoxicology by subject area and or disease, sources of nanomaterials, drug delivery systems and more. Scientists, researchers, and students in all fields that use nanotechnology will find this book essential reading.
Contents
Introduction.- Terminology.- nano.- polymer nanoparticles.- Nonpolymer nanoparticles.- Nanodevices.- Hybrid materials.- Nanocomposite.- Biomedical.- Further Reading.- Historical Development and Future Trends.- introduction.- Early Period.- Premodern period.- Middle Ages.- Modern Nanotechnology.- Regulations.-Scientific Trends.- Future Trends.-Small Systems Big Applications.- Smart Pills.- Beating the Big C.- Further Reading.- Sources and Classifications.- Introduction.- Properties.- Nanomaterials and Bulk Materials.- Sources.- Naturally produced.- Incidental.- Engineered Nanomaterials.-Classifications.- Natural NPs/NMs.- Incidental NPs.- Synthetic (Engineered) Nanomaterials (NMS).- Dimensions Based Nanomaterials.- Nanoparticles.- Nanoclays.- nanoemulsions.- Further Reading.- Synthesis, Detection and Characterization.- Introduction.- Production Approaches.- Synthesis.- Physical Methods.- Chemical Methods.- Biological Approach.- magnetic nps.- Hybrid nanomaterials.- nanocomposites.-Detection.- Characterization and isolation.- Direct Techniques.- indirect Techniques.- Key Issues in Fabrication.- Further Reading.- Mechanisms of Nanotoxicty.- introduction.- Entry Sites and Uptake.- Elimination.- Phagocytosis.- Macropinocytosis.- Other Entry Mechanisms.- Intracellular Trafficking.- Trojan Horse Mechanism.- Cellular Exocytosis.- Cellular Dysfunction.- Inorganic Nanomaterial Toxicity.- Cell Deaths.- Further Readings.- Applications-. Introduction.- Nanoparticle-Based Technologies-. Agriculture.- Energy and Environment.- Materials Science and Engineering.- Materials Science and Engineering.- Health and Medicine.- Hybrid Nanomaterials.- Nanocomposites.- Further Reading.- Nano Based Drug Delivery Systems.- Introduction.- Overview in Biomedical Science.- properties of NP Drug Delivery.- Factors influencing Drug Laden Nanocarriers.- pH Specificity.- Temperature Specificity.- Temperature Specificity.- Advantages of Delivery Vehicles.- Nanocarriers.- Passive Targeting.- Active Targeting.- Uses and Applications.- Delivery Vehicles.- Organic Nanomaterials.-Poly-alkyl-cyano-acrylates (PAC).- Artificial DNA Nanostructures.- Nanocomposites.- Hybrid nanoparticles.- Further Reading.-Tissue Engineering in Dentistry.- Introduction.- Materials for Dental Applications.- Structure and Periodontal Tissue.- Factors Affecting Bone Tissue Regeneration.- Periodontal Diseases.- Tissue Engineering.- Procedure.- Assembly Methods.- Bone Tissue Engineering.- Stem Cell Sources.- Signaling Molecules.- Scaffold/Matrices.- Bioactive Glasses.- Metal-Based materials.- Polymers.- Composites.- Scaffoldfree Techniques.- Biocompatibility.- Drug or Signaling Molecules Delivery.- Future Prospectives.- Further Reading.- Nanobiosensors.- Introduction.- Variations and Types.- Nanoparticle Based Sensors.- Nanotube Based Sensors.- Nanowire Based Sensors.- Components of a typical Biosensors.- Selection and Optimization.- .- Applications.- Cancer.- Detection of diabetes.- Immunoassay (detection of Ab-Ag reaction).- Detection of pathogenic bacteria.- Future Prospects.- Further Reading.- Health and Medicine.- Introduction.- Keywords.- Nanostructures.- Polymers or Organic NPs.- Nonpoymers or Inorganic Nanoparticles.- Health and Medicine.- Neurodegenerative Disorders.- Tuberculosis.- Ophthalmology.- Respiratory diseases.- Surgery.- Toxicity.- Conclusion.- Further Reading Multiple Choice Questions.
