Full Description
A highly disabling infectious disease in developing countries, leprosy, or Hansen's disease, is caused by Mycobacterium leprae, and is still very relevant for the human community due to its transmissible nature, variable presentation and composite clinical picture. Early identification of leprosy and Buruli ulcer (also caused by a Mycobacterium, M. ulcerans) is critical to prevent spreading and patient disability and to establish appropriate therapy.
This richly illustrated, completely revised second edition of Leprosy and Buruli Ulcer describes the characteristic signs of both these diseases, and contents include abnormalities of the skin, nerves, eyes, hands, feet, testes and bone. It also presents the latest diagnostic tools to identify and quantify organ damage to enable readers to recognize and treat this composite systemic disorder, which can represent a true medical emergency if affecting eyes, nerves, and kidneys. Further, it includes additional chapters on leprosy in childhood, prophylaxis and vaccines. For both leprosy and Buruli ulcer, this handy guide helps practitioners and nursing personnel to spot the different clinical manifestations, make a prompt diagnosis and apply effective treatment of both these diseases.
Contents
Foreword.- Preface.- Part I Leprosy: General Section.- 1. History and Phylogeography of Leprosy.- 2. Microbiology of Mycobacterium leprae.- 3. Genetics of Leprosy.- 4. Host Response to Mycobacterium leprae.- 5. Pathogenesis of Leprosy.- 6. Classification of Leprosy.- Part II Leprosy: Patient's Examination.- 7. Leprosy Patient History.- 8. Laboratory Investigations in Leprosy.- Part III Skin.- 9. Physical Examination in Leprosy: Skin.- 10. Clinical Features of Leprosy.- 11. Lucio-Latapí Leprosy.- 12. Histopathology of the Skin in Leprosy [FP1] .- 13. Differential Diagnosis of Leprosy: Skin.- Part IV Leprosy and Nerves.- 14. Peripheral Nerves in Leprosy.- 15. The Leprosy Neuropathy.- 16. Primary Neural Leprosy.- 17. Chronic Neuropathic Pain in Leprosy.- 18. Electrodiagnostic Studies in Leprosy.- 19. Imaging in Leprosy.- 20. Differential Diagnosis of Leprosy: Nerves.- Part V Reactions in Leprosy.-21. Reactions in Leprosy.- 22. Lucio's Phenomenon in Leprosy.- Part VI Leprosy: Systemic Involvement.- 23. Ocular Involvement in Leprosy.- 24. Otolaryngological Manifestations of Leprosy.- 25. Other Organs involved in Leprosy.- Part VII Patient's Management in Leprosy.- 26. Diagnostic Work-Up of Leprosy.- 27. Drugs in Leprosy.- 28. Treatment and Prophylaxis of Leprosy.- 29. Prognosis of Leprosy.- 30. Neurolysis in Leprosy.- 31. Prevention of Disability and Ulcer Care in Leprosy.- 32. Surgical and Social Rehabilitation in Leprosy.- Part VIII Leprosy and Community.- 33. Leprosy in Pregnancy.- 34. Leprosy in Childhood.- 35. Leprosy and HIV/AIDS Co-infection.- 36. Epidemiology of Leprosy.- 37. Leprosy Control.- 38. The Leprosy Mailing List.- Part IX Buruli Ulcer: General Section.- 39. History and geographic distribution of Buruli ulcer.- 40. Microbiology of Mycobacterium ulcerans.- Part X Buruli Ulcer: Patient's Examination.- 41. Laboratory Investigations in Buruli ulcer.- 42. Clinical Features of Buruli ulcer.- 43. Differential Diagnosis of Buruli ulcer.- Part XI Buruli Ulcer: Patient's Management.- 44. Diagnostic Work-up of Buruli ulcer.- 45. Treatment of Buruli ulcer.- 46. Rehabilitation in Buruli ulcer.- Part XII Buruli Ulcer and Community.- 47. Epidemiology of Buruli ulcer.- 48. Buruli ulcer Control.- Subject Index.
