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Full Description
According to the World Health Organization, antimicrobial resistance is a major threat to global health because the number of alternative antibiotics is very limited. Antimicrobial resistance is a slow evolutionary process that has been accelerated by human activities in health, environment and agriculture sectors. Due to their wide application, antibiotics and their residues have been found in almost all food products and natural ecosystems. This book reviews the drivers, impact and mitigation of antimicrobial resistance, with focus on methods and targets.
Contents
Preface.- Chapter 1 - Antimicrobial resistance paradigm and One-health approach.- Chapter 2 - Global surveillance programs on antimicrobial resistance.- Chapter 3 - Antimicrobial resistance, food systems and climate change.- Chapter 4 - In silico approaches for prioritizing drug targets in pathogens.- Chapter 5 - Molecular and systems biology approaches for analyzing drug-tolerant bacterial persister cells.- Chapter 6 - Role of gene editing tool CRISPR-Cas in the management of antimicrobial resistance.- Chapter 7 - Control of bacterial biofilms for mitigating antimicrobial resistance.- Chapter 8 - Intrusion of bacterial quorum-sensing for antimicrobial resistance mitigation: A pharmaceutical perspective.- Chapter 9 - Drug discovery for targeting drug resistant bacteria.
