Full Description
This book presents the latest insights into all the critical aspects of Klinefelter's Syndrome, in order to promote a more homogeneous a medical approach to this condition, leading to better and more "evidence-based" support, and improving patient satisfaction.
It offers physicians and all health professionals involved in treating these patients (andrologists, pediatricians, endocrinologists, psychologists) a comprehensive overview and a useful tool for their daily clinical practice.
Contents
Poetry.- Preface.- 1. Introduction - From a disabling condition to a variant of normalcy.- 2. Epidemiology of an underdiagnosed syndrome.- 3. Causes of the extra chromosome/s.- 4. Different karyotypes, same disease?.- 5. Genetic and epigenetic aspects of the supernumerary X chromosome.- 6. Prenatal Counselling and management in the early neonatal period.- 7. Early developmental pathways and communication good practices.- 8. The diagnosis at prepubertal age.- 9. What to do and when from infancy to puberty.- 10. Neuropsychiatric aspects.- 11. Testicular development.- 12. The Klinefelter puberty.- 13. Genetic of Gametes.- 14. Phenotype of the adulthood.- 15. Hypothalamic-Pituitary Axis Function.- 16. The altered bone.- 17. Obesity, the rule or not.- 18. Lipids and glucose metabolism.- 19. Cardiovascular characteristics.- 20. The Thyroid Function.- 21. Oncological problems.- 22. Fertility preservation.- 23. Fertility vs Infertility.- 24. Psychological features.- 25. Sexual function.- 26. Testosterone treatment in male patients with Klinefelter's syndrome.
