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Full Description
This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.
Contents
Insights into the emergence, clinical prevalence and significance of Staphylococcus aureus small colony variants.- Periprosthetic Joint Infection.- Complications in orthopedic trauma surgery: fracture related infection.- Chiral Stereochemical Strategy for Antimicrobial Adhesion.- Perspectives on and need to develop new infection control strategies.- Battling bacteria with free and surface-immobilized polymeric nanostructures.- Engineering Approaches to Create Antibacterial Surfaces on Biomedical Implants and Devices .- 3D Printed Ceramic-Polymer Composites for Treating Bone Infection.- Bioinspired interfaces for the management of skin infections.- Antimicrobial endodontic materials.- Local Delivery of Anti-biofilm Therapeutics.- Device-Related Infections.- Advances in polysaccharide based antimicrobial delivery vehicles.- Antibacterial Coatings on Medical Implants.- Perspectives on biomaterial-associated infection: pathogenesis and current clinical demands.- Polymeric Nanoparticulate Delivery Vehicles of Antimicrobials for Biofilm Eradication.- Pathogenesis of biomaterial-associated infection.- Metal- and Polymer-Based Nanoparticles for Advanced Therapeutic and Diagnostic System Applications.- Antimicrobial Material in Arthroplasty.- Antimicrobial Hydrogels: Key Considerations and Engineering Strategies for Biomedical Applications.- Antibacterial Polymeric and Peptide Gels/Hydrogels to Prevent Biomaterial-related Infections.- The Impact of Bacterial Biofilms in Transfusion Medicine.- Mechanisms of Action and Chemical Origins of Biologically Active Antimicrobial Polymers.- When the Race is Lost: The Clinical Impact of Prosthetic Joint Infections.- Antibacterial Hydroxyapatite: An Effective Approach to Cure Infections in Orthopedics.- Index.
