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Full Description
This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging. Several of the chapters are from the Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference that was held in June 2018 at McGill University. The authors represent international expertise on a wide variety of topics ranging from different types of cancer (prostate, bone, breast, etc.) to tumor microenvironment, tumor progression, homogeneity, and possible therapies and treatments.
Contents
Mechanisms underlying metastatic pancreatic cancer.- Current Perspectives on Nasopharyngeal Carcinoma.- An in Vitro Model of Triple Negative Breast cancer.- Emerging role of novel biomarkers of Ly6 gene family in pan cancer.- The Oncoprotein Gankyrin/PSMD10 as a Target of Cancer Therapy.- Contributing roles of CYP2E1 and other cytochrome P450 isoforms in alcohol-related carcinogenesis.- Novel Human Prostate Epithelial Cell Cultures.- African American Prostate Normal and Cancer Cells for Health Disparities Research.- Assessing the Advantages, Limitations and Potential of Human Primary Prostate Epithelial Cells as a Pre-Clinical Model for Prostate Cancer Research.- Role of alternative splicing in prostate cancer aggressiveness and drug resistance in African Americans.- Research Article: Discovery of Metabolic Biomarkers Predicting Radiation Therapy Late Effects in Prostate Cancer Patients.- The Aging Skeleton.- Parathyroid Hormone Related Protein (PTHrP): an Emerging Target in Cancer Progression and Metastasis.- Targeting DNA hypomethylation in malignancy by epigenetic therapies.- Tumor Dormancy and Slow-Cycling Cancer Cells.- Resolution of Cellular Heterogeneity in Human Prostate Cancers: Implications for Diagnosis and Treatment.- Small molecule inhibition of glycogen synthase-kinase 3 in cancer immunotherapy.
