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Full Description
Organized and edited by Ivano Bertini, Harry Gray, Ed Stiefel, and Joan Valentine, with contributions from many other world leaders in the field, this all-new book is equally appropriate for graduate or senior undergraduate courses in bioinorganic chemistry. The book has been extensively class-tested at Princeton and UCLA, and it includes tutorials in biology and biochemistry and in inorganic chemistry to aid students of varying backgrounds.
The main text is divided into two parts:
Part A, "Overviews of Biological Inorganic Chemistry," sets forth the unifying principles of the field. A full course in bioinorganic chemistry could be based entirely on this overview section, which is a really a book within a book!
Part B, "Metal-Ion Containing Biological Systems," describes specific classes of systems in detail. A special feature is the strong connection to the genomic revolution that has dramatically enhanced our ability to define the function of gene products in living organisms.
Throughout the book, protein data bank codes are given for structures discussed in the text, and students are encouraged to learn to use the PDB in their courses and research. This exciting new book will be a must read for years to come for all students and researchers interested in the field of biological inorganic chemistry.
Contents
I Introduction and Text Overview
PART A: OVERVIEWS OF BIOLOGICAL INORGANIC CHEMISTRY
II Bioinorganic chemistry and the biogeochemical cycles
III Metal ions and proteins: Binding, stability and folding
IV Special cofactors and metal clusters
V Transport and storage of metal ions in biology
VI Biominerals and biomineralization
VII Metals in medicine
PART B: METAL-ION CONTAINING BIOLOGICAL SYSTEMS
VIII Metal ion transport and storage
IX Hydrolytic chemistry
X Electron transfer, respiration and photosynthesis
XI Oxygen metabolism
XII Hydrogen, carbon, nitrogen, and sulfur metabolism
XIII Metalloenzymes with radical intermediates
XIV Metal ion receptors and signaling
TUTORIALS
Tutorial I Cell biology, biochemistry and evolution
Tutorial II Fundamentals of coordination chemistry
Appendices; Index
