Full Description
Prostate cancer accounts for nearly a quarter of all male cancers, and the incidence is rising as detection rates continue to improve, and life expectancy increases. Timely intervention affords a wider range of management options and in this new volume the editors review the choices available. In the first section lifestyle interventions, such as nutrition and screening, and evaluation of risk factors are discussed; then follows an update on management strategies for localised and locally advanced cancer in various risk groups, drawing on the results of the latest clinical trials. The third section of the book looks at advanced cancer including the management of metastases, and encompasses hormonal and chemotherapy, and palliative care. The volume concludes with a review of common complications of prostate cancer such as urinary obstruction and erectile dysfunction, and appropriate strategies for pain control.
Among the key topics discussed: the evidence for and against PSA screening; the value of current prognostic models in predicting clinical outcomes; the role of biomarkers in evaluating therapeutic success; How to determine the endpoint of clinical trials; and, new horizons in chemotherapy for prostate cancer. This new work addresses questions which challenge every clinician involved with the care of cancer patients today, and provides authoritative insights into the thinking that will define best practice in future.
Contents
Part I: Prevention and Diagnosis; 1. Nutrition, lifestyle interventions and prevention. J Brooks; 2. Clinical markers for prostate cancer. R Getzenberg; 3. Histopathological markers and precursor lesions. D Bostwick; 4. Screening for prostate cancer. P Albertsen; Part II: Regional prostate cancer - localised and locally advanced prostate cancer; 5. Risk categories - therapeutic implications. M Kattan; 6. Conservative strategies. L Klotz; 7. Treatment strategies for low risk prostate cancer. M Soloway; 8. Treatment strategies for high risk prostate cancer. M Feneley, H Payne; 9. Treatment strategies for biochemical recurrence of prostate cancer. V Khoo; Part III: Advanced prostate cancer - distant metastases; 10. Endpoints for clinical trials. K Chi, M Gleave; 11. Hormonal strategies for treatment of advanced disease. D Gillat; 12. Chemotherapy strategies for treatment of advanced disease. M Carducci, A Armstrong; 13. Molecular strategies and future trials for treatment of advanced disease. D Newling; 14. Therapeutics strategies of palliative care and quality of life for advanced prostate cancer. C Farnham, O Al-Salihi, F Lim; Part IV: Management of complications; 15. Treatment strategies for spinal cord compression and fractures. A Stirling; 16. Treatment strategies for urinary obstruction. R Kirby; 17. Treatment strategies for erectile dysfunction. A Burnett; 18. Treatment strategies for pain control. J O'Sullivan; Abbreviations; Index.
