Full Description
Vascular grafts infections persist despite advances in graft materials and new, potent antibodies. The consequences of these infections - loss of limb or loss of life are the main significant problems. Antibiotic-bonded grafts provide protection against infections during the period of greatest vulnerability - the initial weeks following implantation. Experimental results demonstrate gradual improvement in the efficacy of these grafts.
Contents
Vascular graft infections - current status regarding diagnosis and managment; bacteriology and pathogenesis of graft infections; antibiotics used in the prophylaxis of graft infections; graft materials; models of graft infection - development and use; development and results of antibiotic-impregnated vascular grafts; future directions in the development of bacterial resistant grafts.