Full Description
1. Covers the application of stem cell technology.2. The field of stem cell technology is both rapidly developing and controverstial in its applications.3. Medicinal chemists, biochemists, those working in regenerative medicine, pharmacologists.4. Issues in Toxicology series, Biomolecular science series5. This book will focus on the principle non-therapeutic applications of stem cell technology, but will also include the emerging field of soluble, regenerative medicines.
Contents
Preface; Stem cellspathology using genetically engineered ES cells; Reprogramming and induced pluripotency; Modelling CNS disease aspects using IPS cells; IPS screening using patient lines for chronic CNS disorders; IPS screening for monogenic disorders; Small compound libraries HESC; Chemical entities modulating stem cell behaviour; Molecular pathway analysis using tissue stem cell compartments; Endothelial cells and vasculature; Regulation of renewal and repair of epithelial tissues; Strategies for target and drug discovery using NSC; Target identification in the elusive cancer irritating cell; Hepatocyte; Cardiomyocytes; Stem cells, culture adaptation and tetromas; Regenerative pharmacology: emerging concepts and practices; Functional tissue engineering and remodelling with stem cells; Outlook and future perspectives; index
